Tahar Dob

Chemical composition of the essential oil of Artemisia herba-alba Asso grown in Algeria

Abstract The essential oil obtained by hydrodistillation from the aerial parts of Artemisia herba-alba Asso growing wild in Msila-Algeria, was investigated using both capillary GC and GC/MS techniques. The oil yield was 1.02% based on dry weight. Sixty-eight components amounting to 94.7% of the oil were identifed, 33 of them being reported for the frst time in Algerian A. herba-alba oil and 21 of these components have not been previously reported in A. herba-alba oils. The oil contained camphor (19.4%), trans-pinocarveol (16.9%), chrysanthenone (15.8%) and β-thujone (15%) as major components. Monoterpenoids are the main components (86.1%), and the irregular monoterpenes fraction represented a 3.1% yield.

New Dithiolopyrrolone Antibiotics from Saccharothrix sp. SA 233

Three new natural dithiopyrrolone antibiotics, 3-methyl-2-butenoylpyrrothine (1), tigloylpyrrothine (2), and n-butyropyrrothine (3) were isolated along with the known isobutyropyrrothine (4) and thiolutin (5) from the fermentation broth of Saccharothrix sp. SA 233. The structures of the novel compounds were established on the basis on their spectral data.

Chemical composition of the essential oils of Pistacia lentiscus L. from Algeria

Abstract The essential oils of Pistacia lentiscus L. from three regions of Algeria (Algiers, Tizi-Ouzou and Oran) were isolated from aerial parts by hydrodistillation and were investigated by GC and GC/MS. Longifolene was predominant in the oils from Algiers (12.8%) and Tizi-Ouzou (16.4%), while α-pinene (19.0%) was the major constituent of the Oran oil. The other compounds of oils were present in important amounts; Algiers oil: γ-cadinene (6.2%)s, trans-β-terpineol (5.0%) and α-acorneol (4.6%); Tizi-Ouzou oil: trans-β-terpineol (15.6%), terpinen-4-ol (7.0%) and γ-muurolene (5.7%); Oran oil: trans-β-terpineol (13.1%), sabinene (12.6%) and β-pinene (6.5%). A comparison with oils from P. lentiscus of other countries reported in literature shows both qualitative and quantitative differences.

Essential Oil Composition of Lavandula stoechas. from Algeria

Abstract The essential oil of Lavandula stoechas. L. growing spontaneously in Algeria was investigated by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) for the first time. The oil was isolated from the aerial parts of the plant (leaves and flowers) by distillation in a yield of 1.1%. Fifty-four components amounting to ca.. 73% of the oil were identified, the major component being fenchone (31.6%). The other significant constituents were camphor (22.4%), p.-cymene (6.5%), lavandulyl acetate (3.0%), and α-pinene (1.0%). Our results show that the oil consists mainly of oxygenated monoterpenes (62.0%). A comparison with oils from other Lavandula stoechas. from other countries reported in literature shows qualitative and quantitative differences.

Essential Oil Composition of Pinus halepensis Mill. from Three Different Regions of Algeria

Abstract Needles of Pinus halepensis Mill. were collected from three different locations at Sidi Feradj (SF), Djelfa (Dj) and Saïda (Sd) in Algeria. Their oils isolated by hydrodistillation yielding 0.5% from SF, 0.8% from Dj and 0.9% from Sd, have been investigated for their components by means of GC and GC/MS techniques. More then 41 compounds were identified in the needle oils of Sidi Feradj (SF) and Saïda (Sd) and 39 compounds in Djelfa (Dj). The main constituents of three samples of P. halepensis leaf oil were β-caryophyllene (19.8–25.8%), followed by α-humulene (6.2%) in SF and 10.5% in Sd and aromadendrene (8.5%) in Dj, while the third constituents were aromadendrene (4.2%) in SF and α-pinene (5.2%) in Dj and 6.4% in Sd.

Chemical Composition of the Essential Oil of Artemisia campestris. L. from Algeria

Abstract The chemical composition of the hydrodistilled essential oil of the air-dried aerial parts of wild red wormwood (Artemisia campestris. L.) was analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The species is poor in essential oil (yield = 0.1%). Seventy-one constituents representing 57.0% of total oil have been identified. The result show that oxygenated compounds compose the major part of oil (43.7%) and the main components are (Z,E.)-farnesol (10.3%) followed by cedrol (5.4%) and verbenone (3.8%). Toxic ketones such as α.- and β.-thujone are not detected in the oil.

Composition and antimicrobial activity of the essential oil of Thymus fontanesii

Abstract The yield of oil isolated by hydrodistillation from aerial parts of Thymus fontanesii. Boiss. et Reut. (Lamiaceae) growing wild in Djelfa (Algeria) was 0.9%. Analysis of the oil by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) revealed the identification of 47 components accounting for 98.5% of the total oil. The oil was found to be rich in monoterpenes (91.5%) with major constituents being thymol (29.3%), γ.-terpinene (21.7%), p.-cymene (15.9%), and thymol methyl ether (11.4%), while a smaller amount of linalool (4.8%) and β.-caryophyllene (2.9%) were detected. According to the antimicrobial study using the disk diffusion method and the agar dilution assay–minimal inhibitory concentration (MIC), the oil showed strong in vitro. growth inhibition activity against Gram-negative bacteria and antifungal activity. The oil exhibited the maximum antifungal activity against Mucor ramaniamus. (MIC = 0.2 µL/mL).

Volatile Constituents of the Essential Oil of Ruta chalepensis L. subsp. Angustifolia (Pers.) P. Cout.

Abstract The water distilled essential oil from aerial parts of Ruta chelepensis subsp. angustifolia (Pers.) P. Cout was investigated by GC and GC/MS techniques for the first time. The oil yield was 0.27%. It was characterized by a large amount of ketones (57.0%), with 2-undecanone (28.2%), 2-nonanone (20.0%), 2-methyloctyl acetate (12.7%) and 2-methyldecyl acetate (5.8%) being the major constituents found. A comparison with oils from Ruta species from different countries reported in literature shows a similarity in main compound with most species of these plants.

Analysis of Essential Oil from the Needles of Pinus pinaster Growing in Algeria

The needle oil of the Algerian maritime pine (Pinus pinaster Ait.) growing in natural habitats in Sidi Feradj (Algiers region) was obtained by hydrodistillation in 0.3% yield and analyzed by GC and GC/MS. More than 46 compounds amounting to 65.2% of the total oil were identified. The main components were β-caryophyllene (26.6%), allo-aromadendrene (12.5%), and α-humulene (4.3%).

Essential Oil Composition of Juniperus Oxycedrus. Growing in Algeria

Abstract The chemical composition of the essential oil of Juniperus oxycedrus. from Algeria was studied for the first time. The oil was obtained from the leaves of the plant by hydrodistillation and analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) techniques. The yield of essential oil is 0.1%, based on dry weight. Eighty-nine components representing 82.3% of the total oil were identified. The results show that oxygenated monoterpene (41.0%) composes the major part of oil and the main components are trans.-pinocarveol (7.0%), cis.-verbenol (6.3%), and manoyl oxide (6.0%). A comparison with oils from J. oxycedrus. complex (subspecies and varieties) of other countries reported in literature is discussed briefly.