Takeo Satomi

Structure-activity study of herbicidal N-chloroacetyl-N-phenylglycine esters

Abstract N -Chloroacetyl- N -phenylglycine esters were shown to exert various degrees of growth inhibiting activity against young shoots of annual grasses. The activity against the rice plant and barnyard-grass was determined for 58 derivatives where either the aromatic substituent or ester moiety was modified. The structure-activity relationships were analyzed using physicochemical parameters of the molecule such as log P , σ, and E s , and regression analysis. By comparing the correlations derived for the rice plant and barnyard-grass, the selectivity in herbicidal activity is discussed.