Tang Xican
Chinese Academy of Sciences
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Tang Xican.
Drug Development Research | 1996
Zhu Dayuan; Bai Donglu; Tang Xican
This review will discuss several new drugs which were discovered and developed in recent years from traditional Chinese medicines by the Shanghai Institute of Materia Medica. Huperzine A was isolated from Huperzia serrata, a plant used for the treatment of contusion, strain, haematuria, and swelling in Chinese folk medicine. Pharmacological studies have indicated that huperzine A has powerful and reversible anticholinesterase activity. Y‐maze methods have shown that huperzine A improves learning and retrieval processes, and facilitates memory retention. Huperzine A is used to treat patients with myasthenia gravis and Alzheimers disease in China. Sarmentosin, a cyanogenic glucoside was isolated from the whole plant of Sedum sarmentosium. This plant has long been used to treat hepatitis by folk medicine. Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell‐mediated immune responses in mice. The root of Aconitum is well known in traditional Chinese medicine. Many Aconitum alkaloids have been isolated. Most show potent bioactivities, but with severe toxicity. Recently, some alkaloids such as 3‐acetylaconitine, lappaconitine, have shown significant anesthetic activity and exhibit a higher therapeutic index. Guan‐fu base A was isolated from the tuber root of Aconitum coreanum. Guan‐fu base A has antiarrhythmic action and is now in clinical trials. Drug Dev. Res. 39:147–157.
Bioorganic & Medicinal Chemistry Letters | 1998
Zeng Fanxing; Jiang Hualiang; Tang Xican; Chen Kaixian; Ji Ruyun
Abstract The synthesis of (±)-14-Fluorohuperzine A has been accomplished and the ability of this agent to inhibit acetylcholinesterase has been measured. Taking into account its racemic form, this compound exhibits 62 times less potent activity than natural (−)-huperzine A.
Archive | 2003
Cai Maojun; Shen Jingkang; Tang Xican
Chinese Journal of New Drugs and Clinical Remedies | 2006
Tang Xican
Archive | 2014
Zhao Weimin; Zhang Haiyan; Wang Hongmin; Tang Xican; Wu Jian; Ruan Zhi; Li Jinlong; Fu Yan
Chinese Journal of Pharmacology and Toxicology | 1987
Tang Xican
Archive | 2015
Ye Yang; Tang Xican; Zhang Haiyan; Yao Sheng; Wang Wei; Ji Ping
Archive | 2015
Ye Yang; Tang Xican; Zhang Haiyan; Yao Sheng; Wang Wei; Ji Ping
Archive | 2014
Liu Hong; Zhang Haiyan; Zhou Yu; Fu Yan; Jiang Hualiang; Tang Xican; Chen Kaixian
Archive | 2014
Zhang Haiyan; Guo Yuewei; Tang Xican; Gong Jingxu; Wang Wei; Jiang Chengshi