Tânia Leme da Rocha Martinez

A obesidade e sua associação com os demais fatores de risco cardiovascular em escolares de Itapetininga, Brasil

FUNDAMENTO: A escassez de dados sobre a obesidade infantil e o risco cardiovascular no Brasil. OBJETIVO: Determinar a prevalencia de hipertensao, dislipidemia, obesidade e suas correlacoes em uma amostra de escolares de Itapetininga-SP. METODOS: Corte transversal com coleta sistematizada de dados antropometricos (peso, altura, cintura, indice de massa corporal e niveis pressoricos) e dosagens de glicose, colesterol (total e fracoes), acido urico e apolipoproteina A e B, em uma amostra aleatoria, representativa de escolares da rede publica de Itapetininga-SP. Analise dos dados utilizando parâmetros populacionais das curvas do NCHS(2000), categorias de pressao arterial do NHBPEP(2004) e categorias dos niveis sericos de colesterol propostos pela AHA para criancas e adolescentes(2003). RESULTADOS: Um total de 494 criancas e adolescentes participaram do estudo. Dos participantes, 11,7% apresentaram HAS, 51% apresentaram aumento do colesterol total, 40,5% apresentaram aumento do LDL-colesterol, 8,5% apresentaram aumento dos triglicerides e 6,1% tiveram valores baixos de HDL-colesterol. As medias (±desvio padrao) do CT, HDL-colesterol, LDL-colesterol e triglicerides foram respectivamente 172,1(27,9), 48,1(10,0), 105,7(23,1) e 90,9(43,8). A obesidade e o sobrepeso foram detectados em 12,8% e 9,7% da amostra, sendo que a obesidade determinou uma maior chance de se detectar a dislipidemia e a hipertensao quando comparada com os demais grupos. CONCLUSAO: Este estudo fornece subsidios para a hipotese de uma distinta prevalencia de excesso de peso entre escolares da rede publica das regioes nordeste e sudeste, maior nesta ultima. Adicionalmente, demonstra uma associacao da obesidade com a dislipidemia e a hipertensao naquele grupo. Diante da incipiencia de dados no Brasil sobre a questao estudada, o nosso trabalho fornece dados importantes para futuras comparacoes.BACKGROUND Paucity of data on childhood obesity and cardiovascular risk in Brazil. OBJECTIVE To determine the prevalence of hypertension, dyslipidemia, obesity and their correlations in a sample of school children in Itapetininga, State of Sao Paulo, Brazil. METHODS Cross-sectional study with systematic collection of anthropometric data (weight, height, waist circumference, BMI and blood pressure levels) and determination of glucose, total cholesterol, LDL, HDL, uric acid, and apolipoproteins A and B in a random sample representative of school children from the public education system in Itapetininga, State of Sao Paulo. For data analysis, we used population parameters from the NCHS curves (2000), blood pressure categories from NHBPEP (2004), and the serum cholesterol levels proposed by the AHA for children and adolescents (2003). RESULTS A total of 494 children and adolescents participated in the study. Of these, 11.7% had HBP, 51% increased total cholesterol, 40.5% increased LDL-cholesterol, 8.5% increased triglycerides, and 6.1% low HDL-cholesterol levels. Mean (+/- standard deviation) TC, HDL-cholesterol, LDL-cholesterol and triglycerides were 172.1(27.9), 48.1(10.0), 105.7(23.1) and 90.9(43.8), respectively. Obesity and overweight were detected in 12.8% and 9.7% of the sample, respectively. Individuals of the obese group had a greater chance of presenting with dyslipidemia and hypertension in comparison with those of the other groups. CONCLUSION This study supports the hypothesis of different prevalences of excess weight among school children from the public education system of the northeastern and southeastern regions of Brazil, with higher rates in the latter. Additionally, it demonstrates an association of obesity with dyslipidemia and hypertension in that group. In light of the paucity of Brazilian data on this issue, our study provides important data for further comparisons.

Obesity and its association with other cardiovascular risk factors in school children in Itapetininga, Brazil

FUNDAMENTO: A escassez de dados sobre a obesidade infantil e o risco cardiovascular no Brasil. OBJETIVO: Determinar a prevalencia de hipertensao, dislipidemia, obesidade e suas correlacoes em uma amostra de escolares de Itapetininga-SP. METODOS: Corte transversal com coleta sistematizada de dados antropometricos (peso, altura, cintura, indice de massa corporal e niveis pressoricos) e dosagens de glicose, colesterol (total e fracoes), acido urico e apolipoproteina A e B, em uma amostra aleatoria, representativa de escolares da rede publica de Itapetininga-SP. Analise dos dados utilizando parâmetros populacionais das curvas do NCHS(2000), categorias de pressao arterial do NHBPEP(2004) e categorias dos niveis sericos de colesterol propostos pela AHA para criancas e adolescentes(2003). RESULTADOS: Um total de 494 criancas e adolescentes participaram do estudo. Dos participantes, 11,7% apresentaram HAS, 51% apresentaram aumento do colesterol total, 40,5% apresentaram aumento do LDL-colesterol, 8,5% apresentaram aumento dos triglicerides e 6,1% tiveram valores baixos de HDL-colesterol. As medias (±desvio padrao) do CT, HDL-colesterol, LDL-colesterol e triglicerides foram respectivamente 172,1(27,9), 48,1(10,0), 105,7(23,1) e 90,9(43,8). A obesidade e o sobrepeso foram detectados em 12,8% e 9,7% da amostra, sendo que a obesidade determinou uma maior chance de se detectar a dislipidemia e a hipertensao quando comparada com os demais grupos. CONCLUSAO: Este estudo fornece subsidios para a hipotese de uma distinta prevalencia de excesso de peso entre escolares da rede publica das regioes nordeste e sudeste, maior nesta ultima. Adicionalmente, demonstra uma associacao da obesidade com a dislipidemia e a hipertensao naquele grupo. Diante da incipiencia de dados no Brasil sobre a questao estudada, o nosso trabalho fornece dados importantes para futuras comparacoes.BACKGROUND Paucity of data on childhood obesity and cardiovascular risk in Brazil. OBJECTIVE To determine the prevalence of hypertension, dyslipidemia, obesity and their correlations in a sample of school children in Itapetininga, State of Sao Paulo, Brazil. METHODS Cross-sectional study with systematic collection of anthropometric data (weight, height, waist circumference, BMI and blood pressure levels) and determination of glucose, total cholesterol, LDL, HDL, uric acid, and apolipoproteins A and B in a random sample representative of school children from the public education system in Itapetininga, State of Sao Paulo. For data analysis, we used population parameters from the NCHS curves (2000), blood pressure categories from NHBPEP (2004), and the serum cholesterol levels proposed by the AHA for children and adolescents (2003). RESULTS A total of 494 children and adolescents participated in the study. Of these, 11.7% had HBP, 51% increased total cholesterol, 40.5% increased LDL-cholesterol, 8.5% increased triglycerides, and 6.1% low HDL-cholesterol levels. Mean (+/- standard deviation) TC, HDL-cholesterol, LDL-cholesterol and triglycerides were 172.1(27.9), 48.1(10.0), 105.7(23.1) and 90.9(43.8), respectively. Obesity and overweight were detected in 12.8% and 9.7% of the sample, respectively. Individuals of the obese group had a greater chance of presenting with dyslipidemia and hypertension in comparison with those of the other groups. CONCLUSION This study supports the hypothesis of different prevalences of excess weight among school children from the public education system of the northeastern and southeastern regions of Brazil, with higher rates in the latter. Additionally, it demonstrates an association of obesity with dyslipidemia and hypertension in that group. In light of the paucity of Brazilian data on this issue, our study provides important data for further comparisons.

La obesidad y su asociación con los demás factores de riesgo cardiovascular en escolares de Itapetininga, Brasil

FUNDAMENTO: A escassez de dados sobre a obesidade infantil e o risco cardiovascular no Brasil. OBJETIVO: Determinar a prevalencia de hipertensao, dislipidemia, obesidade e suas correlacoes em uma amostra de escolares de Itapetininga-SP. METODOS: Corte transversal com coleta sistematizada de dados antropometricos (peso, altura, cintura, indice de massa corporal e niveis pressoricos) e dosagens de glicose, colesterol (total e fracoes), acido urico e apolipoproteina A e B, em uma amostra aleatoria, representativa de escolares da rede publica de Itapetininga-SP. Analise dos dados utilizando parâmetros populacionais das curvas do NCHS(2000), categorias de pressao arterial do NHBPEP(2004) e categorias dos niveis sericos de colesterol propostos pela AHA para criancas e adolescentes(2003). RESULTADOS: Um total de 494 criancas e adolescentes participaram do estudo. Dos participantes, 11,7% apresentaram HAS, 51% apresentaram aumento do colesterol total, 40,5% apresentaram aumento do LDL-colesterol, 8,5% apresentaram aumento dos triglicerides e 6,1% tiveram valores baixos de HDL-colesterol. As medias (±desvio padrao) do CT, HDL-colesterol, LDL-colesterol e triglicerides foram respectivamente 172,1(27,9), 48,1(10,0), 105,7(23,1) e 90,9(43,8). A obesidade e o sobrepeso foram detectados em 12,8% e 9,7% da amostra, sendo que a obesidade determinou uma maior chance de se detectar a dislipidemia e a hipertensao quando comparada com os demais grupos. CONCLUSAO: Este estudo fornece subsidios para a hipotese de uma distinta prevalencia de excesso de peso entre escolares da rede publica das regioes nordeste e sudeste, maior nesta ultima. Adicionalmente, demonstra uma associacao da obesidade com a dislipidemia e a hipertensao naquele grupo. Diante da incipiencia de dados no Brasil sobre a questao estudada, o nosso trabalho fornece dados importantes para futuras comparacoes.BACKGROUND Paucity of data on childhood obesity and cardiovascular risk in Brazil. OBJECTIVE To determine the prevalence of hypertension, dyslipidemia, obesity and their correlations in a sample of school children in Itapetininga, State of Sao Paulo, Brazil. METHODS Cross-sectional study with systematic collection of anthropometric data (weight, height, waist circumference, BMI and blood pressure levels) and determination of glucose, total cholesterol, LDL, HDL, uric acid, and apolipoproteins A and B in a random sample representative of school children from the public education system in Itapetininga, State of Sao Paulo. For data analysis, we used population parameters from the NCHS curves (2000), blood pressure categories from NHBPEP (2004), and the serum cholesterol levels proposed by the AHA for children and adolescents (2003). RESULTS A total of 494 children and adolescents participated in the study. Of these, 11.7% had HBP, 51% increased total cholesterol, 40.5% increased LDL-cholesterol, 8.5% increased triglycerides, and 6.1% low HDL-cholesterol levels. Mean (+/- standard deviation) TC, HDL-cholesterol, LDL-cholesterol and triglycerides were 172.1(27.9), 48.1(10.0), 105.7(23.1) and 90.9(43.8), respectively. Obesity and overweight were detected in 12.8% and 9.7% of the sample, respectively. Individuals of the obese group had a greater chance of presenting with dyslipidemia and hypertension in comparison with those of the other groups. CONCLUSION This study supports the hypothesis of different prevalences of excess weight among school children from the public education system of the northeastern and southeastern regions of Brazil, with higher rates in the latter. Additionally, it demonstrates an association of obesity with dyslipidemia and hypertension in that group. In light of the paucity of Brazilian data on this issue, our study provides important data for further comparisons.

Alterações no metabolismo da homocisteína induzidas por aguardente de cana-de-açúcar em alcoólatras

Alcoholism is related to malnutrition and low levels of several vitamins that take part in the metabolism of homocystein (HCY). The objective of this study was to analyse the prevalence of hyperhomocysteinaemia in patients with heavy daily intake of sugar-cane liquor. In this study were included 31 hospitalized man for alcoholism treatment. Serum folate (FOL), HCY, vitamin B12 (B12) and liver enzymes were determinated and repeated after 21 days of alcohol withdrawal. The values of HCY in µmol/l before and after treatment were respectivally of 24.88 ± 2.09 and 12.48 ± 0.69. The alcohol abstinence decreased significativally the values of aspartate transaminase, alanine aminotransferase and gamma-glutamyl transpeptidase. There were not alterations in red blood cell count, total protein and hemoglobin corpuscular media concentration. The levels of HCY before treatment are correlated to the FOL (r 2 = 0.333). These results suggested that chronic alcoholism is followed by disturbs of sulphur aminoacid metabolism and that the hyperhomocysteinaemia ethanol-induced by sugar-cane liquor may be accompanied by low serum FOL levels that aggrieves the nutritional status of these patients.