Thelagathoti Hari Babu

Regioselective synthesis and structural elucidation of 1,4-disubstituted 1,2,3-triazole derivatives using 1D and 2D NMR spectral techniques

Regioselective synthesis of 2‐[1‐(2‐oxo‐2‐phenylethyl)‐1H‐[1,2,3]triazol‐4‐ylmethoxy]‐benzaldehyde derivatives was achieved by [3 + 2] cycloaddition reaction of 2‐(prop)‐2‐ynyloxy‐benzaldehyde derivatives with phenacyl azide. The regiochemistry and the spectral assignments of the synthesized triazole derivatives were studied using both 1D and 2D NMR spectral techniques in solution. Copyright