Thomas J. Tucker
Merck & Co.
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Publication
Featured researches published by Thomas J. Tucker.
Tetrahedron Letters | 1990
Wayne J. Thompson; Thomas J. Tucker; John E. Schwering; James L. Barnes
Abstract The palladium catalyzed coupling of allylic acetates with carbon nucleophiles generates urethane protected trans-allylic amines with exceptionally high stereoselectivity.
Bioconjugate Chemistry | 2011
Jeffrey G. Aaronson; Lee Klein; Aaron Momose; Ann M. O’Brien; Anthony W. Shaw; Thomas J. Tucker; Yu Yuan; David M. Tellers
Conditions for facile solution-phase amide conjugation of amine-modified siRNA with a diverse set of carboxylic acid partners using the coupling reagent HATU are described. These conditions eliminate the need for isolated activated esters and allow for rapid access to conjugates with a wide range of lipophilicity and functionality in good yield.
Archive | 1992
Susan F. Britcher; William C. Lumma; Mark E. Goldman; Terry A. Lyle; Joel R. Huff; Linda S. Payne; Martha L. Quesada; Steven D. Young; William M. Sanders; Philip E. Sanderson; Thomas J. Tucker
Archive | 2011
Jeffrey G. Aaronson; Stanley F. Barnett; René Bartz; Steven L. Colletti; Vasant Jadhav; Aaron Momose; Anthony W. Shaw; David M. Tellers; Thomas J. Tucker; Weimin Wang; Yu Yuan
Archive | 1993
Terry A. Lyle; Thomas J. Tucker; Catherine M. Wiscount
Archive | 2005
Theresa M. Williams; Christopher S. Burgey; Thomas J. Tucker; Craig A. Stump; Ian M. Bell
Archive | 2006
Sandeep A. Saggar; John T. Sisko; Thomas J. Tucker; Robert M. Tynebor; Dai-Shi Su; Neville J. Anthony
Archive | 1994
William C. Lumma; Roger M. Freidinger; Stephen F. Brady; Philip E. Sanderson; Dong-Mei Feng; Terry A. Lyle; Kenneth J. Stauffer; Thomas J. Tucker; Joseph P. Vacca
Archive | 2013
David M. Tellers; Steven L. Colletti; Vadim Dudkin; Jeffrey G. Aaronson; Aaron Momose; Thomas J. Tucker; Yu Yuan; Kathleen B. Calati; Lu Tian; Rubina G. Parmar; Anthony W. Shaw; Weimin Wang; Rachel Anne Storr; Marina Busuek; Robert A. Kowtoniuk
Archive | 1995
William C. Lumma; Roger M. Freidinger; Stephen F. Brady; Philip E. Sanderson; Dong-Mei Feng; Terry A. Lyle; Kenneth J. Stauffer; Thomas J. Tucker; Joseph P. Vacca
