Thomas M. Stace

Giant cross-Kerr effect for propagating microwaves induced by an artificial atom

We investigate the effective interaction between two microwave fields, mediated by a transmon-type superconducting artificial atom which is strongly coupled to a coplanar transmission line. The interaction between the fields and atom produces an effective cross-Kerr coupling. We demonstrate average cross-Kerr phase shifts of up to 20 degrees per photon with both coherent microwave fields at the single-photon level. Our results provide an important step toward quantum applications with propagating microwave photons.

Entangled two-photon source using biexciton emission of an asymmetric quantum dot in a cavity

A semiconductor based scheme has been proposed for generating entangled photon pairs from the radiative decay of an electrically pumped biexciton in a quantum dot. Symmetric dots produce polarization entanglement, but experimentally realized asymmetric dots produce photons entangled in both polarization and frequency. In this work, we investigate the possibility of erasing the “which-path” information contained in the frequencies of the photons produced by asymmetric quantum dots to recover polarization-entangled photons. We consider a biexciton with nondegenerate intermediate excitonic states in a leaky optical cavity with pairs of degenerate cavity modes close to the nondegenerate exciton transition frequencies. An open quantum system approach is used to compute the polarization entanglement of the two-photon state after it escapes from the cavity, measured by the visibility of two-photon interference fringes. We explicitly relate the two-photon visibility to the degree of the Bell-inequality violation, deriving a threshold at which Bell-inequality violations will be observed. Our results show that an ideal cavity will produce maximally polarization-entangled photon pairs, and even a nonideal cavity will produce partially entangled photon pairs capable of violating a Bell-inequality.

A Mechano-Electrochemical Model of Radial Deformation of the Capillary Glycocalyx

A mechano-electrochemical theory of the surface glycocalyx on capillary endothelial cells is presented that models the structure as a mixture of electrostatically charged macromolecules hydrated in an electrolytic fluid. Disturbances arising from mechanical deformation are introduced as perturbations away from a nearly electroneutral equilibrium environment. Under mechanical compression of the layer, such as might occur on the passing of stiff leukocytes through capillaries, the model predicts that gradients in the electrochemical potential of the compressed layer cause a redistribution of mobile ions within the glycocalyx and a rehydration and restoration of the layer to its equilibrium dimensions. Because of the large deformations of the glycocalyx arising from passing leukocytes, nonlinear kinematics associated with finite deformations of the layer are accounted for in the theory. A pseudo-equilibrium approximation is invoked for the transport of the mobile ions that reduces the system of coupled nonlinear integro-differential equations to a single nonlinear partial differential equation that is solved numerically for the compression and recovery of the glycocalyx using a finite difference method on a fixed grid. A linearized model for small strains is also obtained as verification of the finite difference solution. Results of the asymptotic analysis agree well with the nonlinear solution in the limit of small deformations of the layer. Using existing experimental and theoretical estimates of glycocalyx properties, the glycocalyx fixed-charge density is estimated from the analysis to be approximately 1 mEq/l, i.e., we estimate that there exists approximately one fixed charge on the glycocalyx for every 100 ions in blood. Such a charge density would result in a voltage differential between the undeformed glycocalyx and the capillary lumen of approximately 0.1 mV. In addition to providing insight into the mechano-electrochemical dynamics of the layer under deformation, the model suggests several methods for obtaining improved estimates of the glycocalyx fixed-charge density and permeability in vivo.

Engineered optical nonlinearity for quantum light sources

Many applications in optical quantum information processing benefit from careful spectral shaping of single-photon wave-packets. In this paper we tailor the joint spectral wave-function of photons created in parametric downconversion by engineering the nonlinearity profile of a poled crystal. We designed a crystal with an approximately Gaussian nonlinearity profile and confirmed successful wave-packet shaping by two-photon interference experiments. We numerically show how our method can be applied for attaining one of the currently most important goals of single-photon quantum optics, the creation of pure single photons without spectral correlations.

An electrochemical model of the transport of charged molecules through the capillary glycocalyx

An electrochemical theory of the glycocalyx surface layer on capillary endothelial cells is developed as a model to study the electrochemical dynamics of anionic molecular transport within capillaries. Combining a constitutive relationship for electrochemical transport, derived from Ficks and Ohms laws, with the conservation of mass and Gausss law from electrostatics, a system of three nonlinear, coupled, second-order, partial, integro-differential equations is obtained for the concentrations of the diffusing anionic molecules and the cations and anions in the blood. With the exception of small departures from electroneutrality that arise locally near the apical region of the glycocalyx, the model assumes that cations in the blood counterbalance the fixed negative charges bound to the macromolecular matrix of the glycocalyx in equilibrium. In the presence of anionic molecular tracers injected into the capillary lumen, the model predicts the size- and charge-dependent electrophoretic mobility of ions and tracers within the layer. In particular, the model predicts that anionic molecules are excluded from the glycocalyx at equilibrium and that the extent of this exclusion, which increases with increasing tracer and/or glycocalyx electronegativity, is a fundamental determinant of anionic molecular transport through the layer. The model equations were integrated numerically using a Crank-Nicolson finite-difference scheme and Newton-Raphson iteration. When the concentration of the anionic molecular tracer is small compared with the concentration of ions in the blood, a linearized version of the model can be obtained and solved as an eigenvalue problem. The results of the linear and nonlinear models were found to be in good agreement for this physiologically important case. Furthermore, if the fixed-charge density of the glycocalyx is of the order of the concentration of ions in the blood, or larger, or if the magnitude of the anionic molecular valence is large, a closed-form asymptotic solution for the diffusion time can be obtained from the eigenvalue problem that compares favorably with the numerical solution. In either case, if leakage of anionic molecules out of the capillary occurs, diffusion time is seen to vary exponentially with anionic valence and in inverse proportion to the steady-state anionic tracer concentration in the layer relative to the lumen. These findings suggest several methods for obtaining an estimate of the glycocalyx fixed-charge density in vivo.

Thresholds for topological codes in the presence of loss.

Many proposals for quantum information processing are subject to detectable loss errors. In this Letter, we show that topological error correcting codes, which protect against computational errors, are also extremely robust against losses. We present analytical results showing that the maximum tolerable loss rate is 50%, which is determined by the square-lattice bond percolation threshold. This saturates the bound set by the no-cloning theorem. Our numerical results support this and show a graceful trade-off between tolerable thresholds for computational and loss errors.

On the motion of a sphere in a Stokes flow parallel to a Brinkman half-space

A three-dimensional analysis is presented of the Stokes flow, adjacent to a Brinkman half-space, that is induced or altered by the presence of a sphere in the flow field that (a) translates uniformly without rotating, (b) rotates uniformly without translating, or (c) is fixed in a shear flow that is uniform in the far field. The linear superposition of these three flow regimes is also considered for the special case of the free motion of a neutrally buoyant sphere. Exact solutions to the momentum equations are obtained in terms of infinite series expansions in the Stokes-flow region and in terms of integral transforms in the Brinkman medium. Attention is focused on the approach to the asymptotic limit as the ratio of Newtonian- to Darcy-drag forces vanishes. From the leading-order asymptotic approximations, implicit recursion relations are derived to determine the coefficients in the series solutions such that those solutions exactly satisfy the boundary and interfacial conditions as well as the continuity equations in both the Stokes-flow and Brinkman regions. For each of the three flow regimes considered, results are presented in terms of the drag force on the sphere and torque about the sphere centre as a function of the dimensionless separation distance between the sphere and the interfacial plane for several small values of the dimensionless hydraulic permeability of the Brinkman medium. Finally, the free motion of a neutrally buoyant sphere is found by requiring that the net hydrodynamic drag force and torque acting on the sphere vanish. Results for this case are presented in terms of the dimensionless translational and rotational speeds of the sphere as a function of the dimensionless separation distance for several small values of the dimensionless hydraulic permeability. The work is motivated by its potential application as an analytical tool in the study of near-wall microfluldics in the vicinity of the glycocalyx surface layer on vascular endothelium and in microelectromechanical systems devices where charged macromolecules may become adsorbed to microchannel walls.

Fault tolerant quantum computation with very high threshold for loss errors

Many proposals for fault tolerant quantum computation (FTQC) suffer detectable loss processes. Here we show that topological FTQC schemes, which are known to have high error thresholds, are also extremely robust against losses. We demonstrate that these schemes tolerate loss rates up to 24.9%, determined by bond percolation on a cubic lattice. Our numerical results show that these schemes retain good performance when loss and computational errors are simultaneously present.

Quantum nondemolition detection of a propagating microwave photon.

The ability to nondestructively detect the presence of a single, traveling photon has been a long-standing goal in optics, with applications in quantum information and measurement. Realizing such a detector is complicated by the fact that photon-photon interactions are typically very weak. At microwave frequencies, very strong effective photon-photon interactions in a waveguide have recently been demonstrated. Here we show how this type of interaction can be used to realize a quantum nondemolition measurement of a single propagating microwave photon. The scheme we propose uses a chain of solid-state three-level systems (transmons) cascaded through circulators which suppress photon backscattering. Our theoretical analysis shows that microwave-photon detection with fidelity around 90% can be realized with existing technologies.

Multiscale photosynthetic and biomimetic excitation energy transfer

Photosynthetic light harvesting provides a natural blueprint for bioengineered and biomimetic solar energy and light detection technologies. Recent evidence [1–11] suggests some individual light harvesting protein complexes (LHCs) and LHC subunits efficiently transfer excitons towards chemical reaction centers (RCs) via an interplay between excitonic quantum coherence, resonant protein vibrations, and thermal decoherence. The role of coherence in vivo is unclear however, where excitons are transferred through multi-LHC/RC aggregates over distances typically large compared with intra-LHC scales [12– 14]. Here we assess the possibility of long-range coherent transfer in a simple chromophore network with disordered site and transfer coupling energies. Through renormalization we find that, surprisingly, decoherence is diminished at larger scales, and long-range coherence is facilitated by chromophoric clustering. Conversely, static disorder in the site energies grows with length scale, forcing localization. Our results suggest sustained coherent exciton transfer may be possible over distances large compared with nearest-neighbour (n-n) chromophore separations, at physiological temperatures, in a clustered network with small static disorder. This may support findings suggesting long-range coherence in algal chloroplasts [2], and provides a framework for engineering large chromophore or quantum dot hightemperature exciton transfer networks.