Tian-Cheng Gao

Mineral-rich Solar Sea Salt Generates Less Oxidative Stress in Rats than Mineral-deficient Salt

Certain solar sea salts have a high content of essential minerals other than NaCl. The effects of minerals in sea salts on oxidative stress in rats were investigated. Mineral-rich salt (MRS) and mineral-deficient salt (MDS) did not scavenge DPPH radicals. When MRS and MDS (equivalent to 1.8 g NaCl/kg/day) and a saline control were orally administered to rats for 7 weeks, MRS group rats showed lower levels of plasma lipid oxidation than MDS group rats. MRS group rats exhibited significantly lower levels of protein carbonyls and 8-hydroxy-2′-deoxyguanosine in the liver than MDS group rats. MRS group rats showed lower protein expression of NF-κB p65 in adipose tissue than MDS group rats. Intake of MRS may generate less oxidative stress than intake of MDS.