Tirtha Ghosh

Antimicrobial activity of various fractions of ethanol extract of Bacopa monnieri Linn. aerial parts

The ethyl acetate and n-butanol fractions of ethanol extract of Bacopa monnieri Linn. aerial parts were screened for antibacterial and antifungal activities by both zone of inhibition study and determination of minimum inhibitory concentration (MIC). The ethyl acetate fraction was found to be more potent than the n-butanol fraction, though both of them were endowed with antimicrobial activity. The present study reveals the potential usefulness of B. monnieri aerial parts in the treatment of various pathogenic diseases as mentioned in the Ayurvedic literature.

Diuretic and antibacterial activity of aqueous extract of Cleome rutidosperma D.C.

Crude aqueous extract of Cleome rutidosperma was investigated for diuretic and antibacterial activity. The diuretic activity was tested in rats at 400 and 600 mg/kg, orally and compared with furosemide (20 mg/kg, intraperitoneally) as the standard. The antibacterial activity was assessed by disc diffusion method against Bacillus subtilis , Bacillus laterosporus , Staphylococcus aureus , Micrococcous luteus, Pseudomonas aeruginosa , Vibrio cholerae , Escherichia coli and Salmonella typhi at concentrations of 100, 200 and 400 µg/disc respectively. Ciprofloxacin (5 µg/disc) was used as reference control for the antibacterial study. The extract was found to possess significant dose dependent diuretic activity and also effective against both gram-positive and gram-negative bacteria in a concentration dependent manner.

Anthelmintic, antimicrobial and antipyretic activity of various extracts of Clerodendrum infortunatum Linn. leaves

In the present study, various extracts of Clerodendrum infortunatum leaves have been studied for its anthelmintic, antimicrobial and antipyretic activities. In the anthelmintic and antipyretic study it was observed that the benzene extract was more potent than the other two extracts (ethanol and aqueous) even though all the three extracts were endowed with both the properties. The study reveals antimicrobial activity of the extracts against the tested strains of microorganisms between concentration ranges of 75 μg/ml and 350 μg/ml and shows effectiveness more against grampositive bacteria than the gram-negative bacteria.