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Tomáš Hudlický

Brock University

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Publication

Featured researches published by Tomáš Hudlický.

Pure and Applied Chemistry | 2010

Recent chemoenzymatic total syntheses of natural and unnatural products: Codeine, balanol, pancratistatin, and oseltamivir

Tomáš Hudlický

Presented here is a short summary of the recent accomplishments in total synthesis in our laboratories. In particular, recent generations of the syntheses of pancratistatin derivatives, codeine, balanol, and oseltamivir (Tamiflu) are described in relation to their common chemoenzymatic origin in toluene-dioxygenase-mediated dioxygenation of aromatic substrates. Perspectives and projections are discussed in the conclusion.

Tetrahedron | 2009

Chemoenzymatic enantiodivergent total syntheses of (+)- and (−)-codeine☆

Hannes Leisch; Alvaro T. Omori; Kevin J. Finn; Jacqueline Gilmet; Tyler Bissett; David Ilceski; Tomáš Hudlický

Collection of Czechoslovak Chemical Communications | 2009

BIOTRANSFORMATIONS OF MORPHINE ALKALOIDS BY FUNGI: N-DEMETHYLATIONS, OXIDATIONS, AND REDUCTIONS

Vigi Chaudhary; Hannes Leisch; Alena Moudra; Blake Allen; Vincenzo De Luca; D. Phillip Cox; Tomáš Hudlický

Advanced Synthesis & Catalysis | 2014

Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate-Derived Agents: Synthesis of Hydromorphone

Brennan Murphy; Ivan Šnajdr; Ales Machara; Mary Ann A. Endoma-Arias; Theocharis C. Stamatatos; D. Phillip Cox; Tomáš Hudlický

Collection of Czechoslovak Chemical Communications | 2005

Toluene Dioxygenase-Mediated Oxidation of Bromo(methylsulfanyl)benzenes. Absolute Configuration of Metabolites and Evaluation of Chemo- and Regioselectivity Trends

Kevin J. Finn; Oksana Pavlyuk; Tomáš Hudlický

European Journal of Organic Chemistry | 2015

Synthesis of Saturated Benzodioxepinone Analogues: Insight into the Importance of the Aromatic Ring Binding Motif for Marine Odorants

Christopher M. Plummer; Robert Gericke; Philip Kraft; Aaron M. Raynor; Jordan Froese; Tomáš Hudlický; Trevor J. Rook; Oliver A. H. Jones; Helmut Hugel

ChemistrySelect | 2017

Model Studies toward the Total Synthesis of Thebaine by an Intramolecular Cycloaddition Strategy

Petr Koukal; Josef Hájíček; Setu Gupta; Tomáš Hudlický

Tetrahedron | 2016

A chemoenzymatic route to chiral siloxanes

Ravi Naoum; Jacqueline P. Séguin; John F. Trant; Mark B. Frampton; Tomáš Hudlický; Paul M. Zelisko

Synthesis | 2016

Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine

Ales Machara; Mary Ann A. Endoma-Arias; Ivana Císařová; D. Phillip Cox; Tomáš Hudlický

Canadian Journal of Chemistry | 2016

Investigation of a new chiral auxiliary derived chemoenzymatically from toluene: experimental and computational study

Ivan Šnajdr; Jordan Froese; Travis Dudding; Pavlína Horáková; Tomáš Hudlický

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Jordan Froese

Brock University

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Ales Machara

Brock University

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Hannes Leisch

Brock University

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Ivan Šnajdr

Brock University

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Kevin J. Finn

Brock University

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Mary Ann A. Endoma-Arias

Brock University

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Christopher M. Plummer

RMIT University

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Helmut Hugel

RMIT University

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Oliver A. H. Jones

RMIT University

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Trevor J. Rook

RMIT University

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