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The Japanese Medical Journal | 1948

EXPERIMENTAL STUDY ON MEASLES VIRUS

Seiji Arakawa; Jo Hoshino; Hisao Nagashima; Tiaki Kaneko; Tomio Seki

1. The measles virus can be isolated and fixed to mouse after 5 to 8 serial passages on to the chorio-allantoic membrane of developing chick embryo. Such results were obtained with one strain in 1955, and with five strains in 1957. No virus was isolated by intracerebral inoculation with control saline-passaged chick embryo material to mice of the same litter as used for inoculation of the patients serum passaged material. 2. The newly isolated strains showed common antigenicity with Ohki strain isolated and identified in 1951 by virus neutralization and complement fixation tests. 3. Sera taken from patients with the lapse of days, showed the rise and fall of neutralizing and complement fixing antibodies against the mouseadapted measles virus. The measles virus can be isolated and fixed to mouse after 5 to 8 serial passages on to the chorio-allantoic membrane of developing chick embryo. Such results were obtained with one strain in 1955, and with five strains in 1957. No virus was isolated by intracerebral inoculation with control saline-passaged chick embryo material to mice of the same litter as used for inoculation of the patients serum passaged material. The newly isolated strains showed common antigenicity with Ohki strain isolated and identified in 1951 by virus neutralization and complement fixation tests. Sera taken from patients with the lapse of days, showed the rise and fall of neutralizing and complement fixing antibodies against the mouseadapted measles virus.


Archives of Virology | 1956

Untersuchungen ber Trachom: IV. Mitteilung: Nachweis von trachomspezifischen Einschlukrperchen im Hhnerembryo

Seiji Arakawa; Tiaki Kaneko; Tomio Seki

1. Menschliches oder murin adaptiertes Trachomvirus kann durch die Verimpfung auf die Chorioallantois-Membran auf Hühnerembryonen übertragen werden, falls die Bebrütung der Eier bei erniedrigter Temperatur (+ 35–36° C) vorgenommen wird. 2. Die Infektion der Hühnerembryonen manifestiert sich im Auftreten von conjunctivalen Einschluβlörperchen sowie von Initialkörperchen nach Lindner. 3. Der trachomspezifische Charakter der erzeugten Einschluβkörperchen konnte durch die erfolgreiche Hemmung mit Immunseren verschiedener Provenienz nachgewiesen werden. Menschliches oder murin adaptiertes Trachomvirus kann durch die Verimpfung auf die Chorioallantois-Membran auf Hühnerembryonen übertragen werden, falls die Bebrütung der Eier bei erniedrigter Temperatur (+ 35–36° C) vorgenommen wird. Die Infektion der Hühnerembryonen manifestiert sich im Auftreten von conjunctivalen Einschluβlörperchen sowie von Initialkörperchen nach Lindner. Der trachomspezifische Charakter der erzeugten Einschluβkörperchen konnte durch die erfolgreiche Hemmung mit Immunseren verschiedener Provenienz nachgewiesen werden.


Archive | 1980

Pharmaceutical compositions useful as cellular immunopotentiator and antitumor agent and process for production thereof

Seiji Arakawa; Tomio Seki; Hidekazu Matsuoka; Hatsunori Harada; Michinari Ninomiya


Archive | 1980

Pharmaceutical compositions useful as cellular immunopotentiator and anti-tumor agent, process for production thereof and microorganism used therein

Seiji Arakawa; Hidekazu Matsuoka; Tomio Seki; Hatsunori Harada; Michinari Ninomiya


Japanese Journal of Microbiology | 1960

EXPERIMENTAL STUDIES ON EQUINE INFECTIOUS ANEMIA (EIA)

Seiji Arakawa; Tiaki Kaneko; Tomio Seki; Susumu Muto


Japanese Journal of Microbiology | 1960

Experimental studies on equine infectious anemia (EIA). V. Complement fixation test and precipitation test of horse-serum with mouse-fixed EIA virus antigen.

Seiji Arakawa; Tiaki Kaneko; Susumu Muto; Noboru Tsurumi; Katutosi Murakami; Tomio Seki


Japanese Journal of Microbiology | 1960

EXPERIMENTAL STUDIES ON EQUINE INFECTIOUS ANEMIA (EIA):IV. ALTERATION OF BLOOD IN MOUSE INOCULATED WITH THE MOUSE-FIXED EQUINE INFECTIOUS ANEMIA VIRUS AND RE-TRANSMISSION TEST OF THE VIRUS TO A PONY

Seiji Arakawa; Susumu Muto; Tsunehiko Muraoka; Noboru Tsurumi; Tiaki Kaneko; Tomio Seki


Japanese Journal of Microbiology | 1960

EXPERIMENTAL STUDIES ON HEPATITIS INFECTIOSA:REPORT I CULTIVATION OF VIRUS IN THE HEN'S EGG AND FIXATION INTO THE MOUSE BRAIN

Seiji Arakawa; Tsunehiko Muraoka; Tiaki Kaneko; Tomio Seki; Nobumasa Goto


Archives of Virology | 1960

4th Report: Adaptation of the Virus to Mouse-brain, especially after Serial Passages through Chick Embryo Cultures

Seiji Arakawa; Jo Hoshino; Hisao Nagashima; Tiaki Kaneko; Tomio Seki


Japanese Journal of Microbiology | 1957

Studies on Epidemic Diarrhea of Weanling in Japan (Ito's Pseudocholera Infantum) Isolation and Identification of Virus from the Feces or Serum of Patients.

Seiji Arakawa; Takenori Sato; Isamu Kondo; Tiaki Kaneko; Tomio Seki; Teruji Shinozuka; Takao Sakata; Jushichiro Naito

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