Tongxing Wu

The synthesis of l-(+)-homophenylalanine hydrochloride

Abstract l -(+)-Homophenylalanine hydrochloride was synthesized from N-phthaloyl- l -(−)-asparitc anhydride 2 in three steps in 55% overall yield with 99% ee.

Synthesis of C-7 oxidized abietane diterpenes from racemic ferruginyl methyl ether

A series of naturally occurring C-7 oxidized abietane diterpenes have been synthesized from racemic ferruginyl methyl ether in high yields. 6-Hydroxyl-5,6-dehydrosugiol (7) can be converted into stable xanthoperol (12) using high temperature. Among the products, the structures of sugiyl methyl ether (2) and 6(-hydroxysugiyl methyl ether (8) were determined by X-ray analysis.

Enantioselective synthesis of (+)-nuciferal, (+)-(E)-nuciferol and (+)-α-curcumene by chiral hydrogenesterification reaction

Using chiral hydrogenesterification reaction as the key step, the stereoselective synthesis of (+)-nuciferal 1, (+)-(E)-nuciferol 2 and (+)-a-curcumene 3 has been achieved.

ENANTIOSELECTIVE TOTAL SYNTHESES OF 13-ACETYL- 12-HYDROXY-PODOCARPANE- 8,11,13-TRIENE-7-ONE

ABSTRACT A enantioselective total synthetic route to (+)-13-acteyl-12-hydroxy-podocarpane-8,11,13-triene-7-one 1a and (−)-13-acetyl-12-hydroxy-podocarpane-8,11,13-triene-7-one 1b from (S)-(−)-α-cyclocitral 8a and (R)-(+)-α-cyclocitral 8b was developed.

Facile enantioselective synthesis of 6R-(+)-goniothalamin and (6R, 7R, 8R)-(+)-goniothalamin oxide

Facile enantioselective total syntheses of 6R-(+)-goniothalamin 1 and (6R, 7R, 8R)-(+)-goniothalamin oxide 2 were achieved through the Sharpless kinetic resolution of racemic secondary 2- furylmethanol 3 in a short synthetic route.

Stereoselective synthesis of (+)-Δ 5 -dehydrosugiyl methyl ether

A stereoselective synthetic route to (+)-D 5-dehydrosugiyl methyl ether 1 was developed from (S)-(-)-α-cyclocitral 6 in which DDQ as a better oxidant for enone was used.

[4‐Bromo‐2‐(pyridin‐2‐yl­methyl­imino­methyl)­phenolato‐κ3O,N,N′]­methoxocobalt(III) perchlorate

The title Schiff base compound, [Co( C13H10BrN2O)( CH3O)] ClO4, is a mononuclear cobalt(III) compound. The Co-III ion is coordinated by two N atoms and one O atom from a Schiff base ligand, and by another O atom from a coordinated methanolate ligand, giving an approximately square-planar geometry.

Studies on BF 3 .Et 2 O-catalysed cyclisation of 2-aryl-1-(2,4,4- trimethyl-1-cyclohexen-3-yl)-ethanone

Cis-fused products were obtained in high yield from the cyclisations of a series of 2-aryl-1-(2,4,4-trimethyl-1-cyclohexen-3-yl)-ethanones bearing electron donating groups with BF3·Et2O as catalyst.