Torsten Wiemann

Extension of the β gall, 1-transfer to N-acetyl 5-thio-gentosamine by galactosyltransferase

Abstract Galactosyltransferase (GalT) was found to transfer β -galactose to the β -anomeric position of N -acetyl-5-thio-gentosamine to afford a novel β, β (1, 1)-linked disaccharide in 40% yield.

Transfer of galactose to the anomeric position of N-acetyl gentosamine by galactosyltransferase from bovine milk

Galactosyltransferase was found to transfer β-galactose to the β-anomeric position of N-acetyl gentosamine to afford a β,β(1,1)-linked disaccharide. The reaction was generalized supposing an N-acetyl recognition site in the active site.

Synthesis of deoxy derivatives of the glucosinolates glucotropaeolin and glucobrassicin

Abstract The syntheses of 3,4,6- tri -O- acetyl-2-deoxy-1-thio- d -arabino- hexopyranose , 2,4,6- tri -O- acetyl-3-deoxy-1-thio-β- d -ribo- hexopyranose , 2,3,6- tri -O- benzoyl-4-deoxy-1-thio-β- d -xylo- hexopyranose , and 2,3,4- tri -O- acetyl-6-deoxy-1-thio-β- d -glucopyranose are reported. These thiols were coupled with phenylacetohydroximoyl chloride or indol-3-ylacetohydroximoyl chloride, respectively. Sulfation and subsequent deprotection yielded the corresponding deoxy derivatives of glucotropaeolin and glucobrassicin, two major representatives of the glucosinolate family.