Toshiro Shibuya

Electron Microscopic Observation of Eosinophils Migrated to the Thoracic Cavity of Litomosoides carinii-lnfected Mice

In order to study the role of eosinophils in filarial infection, ddY mice were inoculated with 20 Litomosoides carinii 7-day larvae each by the artificial pneumothorax technique. Mi

A Case of Schistosomiasis Suspected by Circumoval Precipitin Test and Diagnosed by Rectal Biopsy

A forty-year-old female from Brazil was admitted to Teikyo Hospital because of easy fatigability, fullness of the abdomen and left hyochondralgia. She was anxious about Schistosoma mansoni infection, because three of her relatives died of the infection. Physical examinations revealed a tenderness at the left hypochondrium. Laboratory data showed no abnormal finding. No egg of S. mansoni was found in the stool. A circumoval precipitin test (COPT) with the serum showed a deposite around the egg. Enzyme-linked immunosorbent assay (ELISA) revealed the presence of antibody against S. mansoni in the serum. A colonoscopy showed no abnormal finding macroscopically. The rectal biopsy showed the existence of mild procitis. The diagnosis was made by finding the characteristic lateral-spined eggs in the biopsy specimens from the rectum. Treatment of 3 g of prazicantel per day for three days was started. She complained of mild nausea at the first dosing. A month later, another three-day-treatment was given. In the case where there are no eggs found in the stool, COPT and ELISA are usefull in detecting the disease, and colonoscopy is recommended in diagnosing the disease.