Toshiyuki Kurihara

Magnesium cyclopropylidenes generated from 1-chlorocyclopropyl phenyl sulfoxides with Grignard reagents: their properties, and a sulfoxide version of the Doering–Moore–Skattebol reaction

Abstract Magnesium cyclopropylidenes were generated from 1-chlorocyclopropyl phenyl sulfoxides with Grignard reagents (EtMgCl or i -PrMgCl) in THF at −78°C in high yields by a sulfoxide–magnesium exchange reaction. The generated magnesium cyclopropylidenes were found to be stable at below −60°C for at least 3xa0h. It was also found that the pyramidal inversion of the magnesium carbenoid was quite slow at below −60°C. When the sulfoxide–magnesium exchange reaction was conducted with phenylmagnesium chloride at 0°C, the 1-chlorocyclopropyl phenyl sulfoxides gave allenes in good to high yields.

One-carbon ring enlargement of lactones

Abstract Two-step or three-step one-carbon ring enlargement of lactones is realized from lactones and chloromethyl phenyl sulfoxide via a rearrangement of alkylidene carbenoid followed by intramolecular cyclization of the ω-hydroxyalkyl ketene intermediate or via a 2-pyridinethiol ester.

Combined Effects of Stretching and Resistance Training on Ankle Joint Flexibility

The purpose of the present study was to clarify the combined effects of stretching and resistance training on the active and passive dorsiflexion range of motion of ankle joint. Sixteen young adult men were randomly assigned to a training () or a control () group. The training group trained one leg for the combined program of static calf stretching and dorsiflexors resistance training program (STR