Toyomichi Shimada
Asahi Glass Co.
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Publication
Featured researches published by Toyomichi Shimada.
Tetrahedron | 1995
Yasushi Matsumura; Toyomichi Shimada; Toshiaki Nakayama; Masahiro Urushihara; Tomoyuki Asai; Yoshitomi Morizawa; Arata Yasuda
Abstract Synthesis of new stable fluoroprostacyclins, 7-fluoro-2,4-methylene-17, 20-dimethylprostacyclins (1,2) with potent and long-lasting anti-anginal activities has been achieved. The cyclobutylene prostaglandin skeleton 10 was constructed efficiently according to three-component coupling reaction. Stereospecific fluorination of silyl ether 11 and subsequent cyclization of the fluoride 12 successfully provided the desired 7-fluoro-2,4-methylene-17,20-dimethylprostacyclin.
Tetrahedron Letters | 1995
Tomoyuki Asai; Yoshitomi Morizawa; Toyomichi Shimada; Toshiaki Nakayama; Masahiro Urushihara; Yasushi Matsumura; Arata Yasuda
Abstract Synthesis of new stable fluoroprostacyclins, 7-fluoro-2,4-methylene-17,20-dimethylprostacyclins ( 1, 2 ) with potent and long-lasting anti-anginal activities has been achieved via three-component coupling reaction and stereospecific fluorination.
Archive | 2003
Shuichiro Sugimoto; Minako Shimada; Toyomichi Shimada; Ryuji Seki; Takashige Maekawa
Archive | 1999
Toyomichi Shimada; Takashige Maekawa
Archive | 1996
Toyomichi Shimada; Yuichi Ohmori; Takashige Maekawa
Archive | 1998
Toyomichi Shimada; Akane Sanekata; Takashige Maekawa
Archive | 1999
Toyomichi Shimada; Takashige Maekawa
Archive | 1999
Toyomichi Shimada; Yuichi Omori; Takashige Maekawa
Archive | 2000
Toyomichi Shimada; Takashige Maekawa
Archive | 1998
Toyomichi Shimada; Kyoichi Kaneko; Shuichiro Sugimoto; Takashige Maekawa
