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Tsunehiro Harada

Kanazawa University

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Publication

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Tetrahedron Letters | 1982

Synthesis of 3-methylisoguanosine, a positional isomer of pharmacologically active nucleosides from marine animals

Taisuke Itaya; Tsunehiro Harada

3-Methylisoguanosine (4c) has been synthesized from 5-(cyanomethylamino)-1(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-carboxamide (1b) through the carbonitrile (2b).

Journal of The Chemical Society, Chemical Communications | 1984

Hydrolysis of nucleosides related to wyosine

Taisuke Itaya; Tsunehiro Harada

The glycosidic bond of 3-β-D-ribofuranosylwye (1) has been found to undergo not only hydrogen ion catalysed cleavage but also general base catalysed or nucleophilic cleavage; steric assistance has been shown to account for its unusual susceptibility to acid.

Journal of Medicinal Chemistry | 1996

2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[d]imidazoles as a novel class of gastric H+/K+-ATPase inhibitors.

Masaki Yamada; Takeshi Yura; Masamichi Morimoto; Tsunehiro Harada; Koichiro Yamada; Yasushi Honma; Mine Kinoshita; Masaki Sugiura

Chemical & Pharmaceutical Bulletin | 1985

Synthesis of 3-β-D-Ribofuranosylwye, the Most Probable Structure for Wyosine from Torulopsis utilis Phenylalanine Transfer Ribonucleic Acid

Taisuke Itaya; Hiroo Matsumoto; Tomoko Watanabe; Tsunehiro Harada

Chemical & Pharmaceutical Bulletin | 1992

A New Synthetic Route to 1, 5-Benzothiazepines. Synthesis of Derivatives of Diltiazem

Tsunehiro Harada; Masamichi Morimoto; Masaaki Nagasawa; Norio Takamura; Hirozumi Inoue; Tokuro Oh-Ishi; Mikio Takeda

Chemical & Pharmaceutical Bulletin | 1989

3-Methylisoguanosine : Synthesis and Acidic Hydrolysis of the Glycosyl Bond

Taisuke Itaya; Tsunehiro Harada

Chemical & Pharmaceutical Bulletin | 1994

Synthesis of the metabolites of clentiazem

Hirozumi Inoue; Susumu Nakamura; Hisao Otsuka; Mitsunori Gaino; Tsunehiro Harada; Kenji Matsuki; Mikio Takeda

Chemical & Pharmaceutical Bulletin | 1989

Synthesis of 5-(Alkylamino)-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamides : Key Intermediates for the Synthesis of 3-Alkyl-9-β-D-ribofuranosylpurine Derivatives

Taisuke Itaya; Tohru Saito; Tsunehiro Harada; Seiya Kagatani; Tozo Fujii

Archive | 1988

Foerfarande Foer framstaellning of 1.5-bensotiazepinderivat.

Hirozumi Inoue; Tsunehiro Harada; Masaaki Nagasawa

ChemInform | 1984

Hydrolysis of Nucleosides Related to Fluorescent Minor Components of Phenylalanine Transfer Ribonucleic Acids.

Taisuke Itaya; Tsunehiro Harada

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Taisuke Itaya

University of Tokyo

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Hirozumi Inoue

National Institutes of Health

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Masaaki Nagasawa

Hokkaido University

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Mikio Takeda

Kyoto University

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Seiya Kagatani

Kanazawa University

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Tohru Saito

University of Tokyo

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Hiroo Matsumoto

Kanazawa University

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Kenji Matsuki

Chiba University

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Norio Takamura

University of Tokyo

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Tokuro Oh-Ishi

University of Tokyo

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