Tunay Karan

Allium vineale Bitkisinden İzole Edilen Flavonoidler Üzerinde Teorik Çalışmalar

Allium vineale ’dan izole edilen kiseriol-7-O-[2-O-E-ferulil]- β -D-glukosit ( 1 ), kiseriol ( 2 ) ve isorhamnetin-3- β -D-glukosit (3) bilesiklerinin kimyasal ozellikleri teorik olarak arastirildi. Bu bilesiklerin kimyasal ozellikleri hesaplanirken RHF/STO-3G metodu kullanildi. Bilesiklerin optimizasyonu ve sonuclarin degerlendirilmesi bu metodla gerceklestirildi. Bilesiklerin ozellikleri ortaya kondu, ayrica teorik ve deneysel sonuclarin karsilastirilmasi ile ilgili bilesiklerin degisik alanlardaki kullanimlari arastirildi. Bilesiklerin antioksidan ozellikleri daha once rapor edildi. Hesaplamalar, kiseriol ( 2 ) bilesiginin kararsiz ve radikal bilesiklerle tepkime verme egiliminde oldugunu gosterdi. Ozetle, antioksidan bilesikler radikal bilesiklere kolaylikla hidrojen vermektedir.

Screening of norharmane from seven cyanobacteria by high-performance liquid chromatography

Background: Cyanobacteria, including pharmaceutically and medicinally valuable compounds attract the great attention lately. Norharmane (9H-pyrido (3,4-b) indole found in some cyanobacteria revealed a great number of biological effects. Objective: Seven cyanobacteria were isolated and identified from Yesilirmak River and Gaziosmanpasa University Campus to determine the norharmane content. Materials and Methods: Cyanobacteria collected from Tokat, Turkey were isolated and identified by morphologically. Norharmane (9H-pyrido [3,4-b] indole) quantities were presented for seven cyanobacteria, Chroococcus minutus (Kütz.) Nägeli, Geitlerinema carotinosum (Geitler) Anagnostidis, Nostoc linckia Bornet ex Bornet and Flahault, Anabaena oryzae F. E. Fritsch, Oscillatoria limnetica Lemmermann, Phormidium sp. Kützing ex Gomont, and Cylindrospermum sp. Kutzing ex E. Bornet and C. Flahault by high-performance liquid chromatography. Results: The norharmane amount indicated for cyanobacterial culture media altered in a species-dependent kind in the range of 0.81–10.87 μ g/g. C. minutus produced the most norharmane among the investigated cyanobacteria as 10.87 μ g/g. Conclusion: Cyanobacteria could be an important source of norharmane as well as pharmaceutically valuable compounds. Abbreviations used: HPLC: High performance liquid chromatograph.