Uko Effiong Udodong
Eli Lilly and Company
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Publication
Featured researches published by Uko Effiong Udodong.
Tetrahedron Letters | 1998
Uko Effiong Udodong; William Wilson Turner; Bret A. Astleford; Frank Brown; Marcella T. Clayton; Steven E. Dunlap; Scott Alan Frank; John L. Grutsch; Lisa Marie Hammond Lagrandeur; Daniel Edward Verral; John Arnold Werner
Abstract Phosphorylation of LY303366 ( 1 ) was studied in THF and DMF. Benzyl phosphate 2 could be prepared in excellent yield using LiOH as the base. Both 2 and the derived phosphonic acid monosodium salt 3 were prone to undergo hydrolytic dephosphorylation.
Tetrahedron | 2003
Uko Effiong Udodong; Marvin M. Hansen; Daniel Edward Verral; Allen R. Harkness; John L. Grutsch; William David Miller; Bret A. Astleford
Abstract Echinocandin B (ECB) analog 1c was methylphosphonylated with the new reagent dimethyldiphosphonate 7 . Selective functionalization of the phenol group was achieved in the presence of 11 other reactive alcohol and amide groups. The phosphonylation was best conducted in a mixture of THF and DMF using lithium t-butoxide as base. Methylphosphonate diester 1d was deprotected by hydrogenolysis to afford methylphosphonate monoester 1e , a potential prodrug for ECB analog 1c .
Organic Process Research & Development | 2006
Nicholas A. Magnus; Michael A. Staszak; Uko Effiong Udodong; James P. Wepsiec
Archive | 1998
John L. Grutsch; Marvin M. Hansen; Allen R. Harkness; Uko Effiong Udodong; Daniel Edward Verral
Archive | 1997
John Brennan; Christopher William Doecke; Perry Clark Heath; Lawrence Edward Patterson; Uko Effiong Udodong; Leland Otto Weigel
Bioorganic & Medicinal Chemistry Letters | 2006
Alan M. Warshawsky; Charles A. Alt; Joseph T. Brozinick; Allen R. Harkness; Eric Hawkins; James Robert Henry; Donald P. Matthews; Anne Reifel Miller; Elizabeth A. Misener; Chahrzad Montrose-Rafizadeh; Gary A. Rhodes; Quanrong Shen; Jennifer Ann Vance; Uko Effiong Udodong; Minmin Wang; Tony Y. Zhang; Richard W. Zink
e-EROS Encyclopedia of Reagents for Organic Synthesis | 2001
Uko Effiong Udodong
e-EROS Encyclopedia of Reagents for Organic Synthesis | 2001
Uko Effiong Udodong
Archive | 1998
Vincent Mancuso; Freddy Andre Napora; Uko Effiong Udodong; Edward Verral Ii Daniel
Archive | 1998
Vincent Mancuso; Freddy Andre Napora; Uko Effiong Udodong; Daniel Edward Verral
