V. Pavan Kumar

Supramolecular Synthesis of 3-Indolyl-3-hydroxy Oxindoles under Neutral Conditions in Water

Various 3-indolyl-3-hydroxy oxindoles were prepared for the first time by supramolecular catalysis involving the reaction of beta-CD:isatin complexes with indoles under neutral conditions in water. beta-Cyclodextrin can be recovered and reused a number of times without loss of activity.

Noble Metal Promoted CeO2–ZrO2-Supported Ni Catalysts for Liquid-Phase Hydrogenation of Cinnamaldehyde

Pd or Pt promoted CeO2–ZrO2-supported Ni catalysts exhibited superior catalytic activity to the hitherto known Ni catalysts for liquid-phase hydrogenation of cinnamaldehyde at moderate conditions. Under similar experimental conditions, the unpromoted catalyst was selective for hydrocinnamaldehyde product (C=C hydrogenation) whereas the promoted catalyst yielded 3-phenyl propanol (C=C and C=O hydrogenation product). Enhanced dispersion of Ni was the cause for higher activity of the promoted Ni catalysts.Graphical AbstractNi/CeO2–ZrO2 promoted with Pd/Pt showed high catalytic activity for liquid phase hydrogenation of cinnamaldehyde. The activity of these catalysts is superior to the hitherto known Ni catalysts.

Synthesis of Thiazoles and Aminothiazoles from β‐Keto Tosylates under Supramolecular Catalysis in the Presence of β‐Cyclodextrin in Water

Abstract This is the first report on the supramolecular synthesis of thiazoles/aminothiazoles from β‐keto tosylates and thioamide/thiourea in water in the presence of β‐cyclodextrin in impressive yields. Formation of inclusion complexes was explained from 1H NMR studies.

ZnCl2 : Simple and efficient catalyst for the allylation of aldehydes with allyltributylstannane

Abstract A simple and efficient procedure for the allylation of aldehydes with allyltributylstannane promoted by zinc chloride under mild conditions to give the corresponding homoallylic alcohols is reported in excellent yields. IICT Communication No. 050702.

Efficient regioselective ring opening of oxiranes with thioacids in the presence of β-cyclodextrin in water

Abstract A mild and convenient synthesis of β‐hydroxy thioesters has been achieved by the regioselective ring opening of oxiranes using thioacetic acid and thiobenzoic acid in the presence of β‐cyclodextrin in water at room temperature. β‐Hydroxy thioesters are realized in high yields, and β‐cyclodextrin can also be recovered and reused. IICT Communication No. 060302.

Organic Reactions in Water: Synthesis of Phenacyl Esters from Phenacyl Bromide and Potassium Salts of Aromatic Acids in the Presence of β‐Cyclodextrin

Abstract A convenient and facile synthesis of phenacyl esters is reported by the reaction of phenacyl bromide with potassium salts of aromatic acids in the presence of β‐cyclodextrin in water under neutral conditions. IICT Communication 050211.