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Volker Eiermann

Merck & Co.

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Featured researches published by Volker Eiermann.

Tetrahedron | 1991

A CONVENIENT APPROACH TO HYDROXYETHYLENE DIPEPTIDE ISOSTERES AS BUILDING BLOCKS FOR ENZYME INHIBITORS

Hans-Eckart Radunz; Volker Eiermann; Günther Dr. Schneider; Angelika Riethmüller

Abstract γ-Lactones 6,8,10 and the ester 9, precursors to the hydroxyethylene dipeptide isostere unit, were synthesized stereoselectively in two or three steps from α-amino-ketones in good yield. Peptides containing these isosteres are potent inhibitors of certain aspartyl proteinases. Alkylation of the (3S,4S)-substituted γ-lactone 6 afforded exclusively cis-alkylation, with regard to C-2 and C-4.

Journal of Medicinal Chemistry | 1990

4-Heterocyclyloxy-2H-1-benzopyran potassium channel activators.

Rolf Bergmann; Volker Eiermann; Rolf Gericke

Archive | 2003

Use of 4 amino-quinazolines as anti cancer agents

Gerhard Barnickel; Hans-Michael Eggenweiler; Volker Eiermann; Rolf Gericke; Wilfried Rautenberg; Christian Sirrenberg; Burkhard Scharm

Archive | 2001

Use Of Thienopyrimidines

Hans-Michael Eggenweiler; Volker Eiermann

European Journal of Organic Chemistry | 1988

Eine effiziente und stereoselektive Synthese von D-erythro-Sphingosin

Hans-Eckart Radunz; Ralf Devant; Volker Eiermann

Journal of Medicinal Chemistry | 1992

Synthesis and dopaminergic activity of some 3-(1,2,3,6-tetrahydro-1-pyridylalkyl)indoles. A novel conformational model to explain structure-activity relationships

Henning Boettcher; Gerhard Barnickel; Hans Heinrich Hausberg; Anton F. Haase; Christoph Seyfried; Volker Eiermann

Chemische Berichte | 1994

Metal Complexes with Tetrapyrrole Ligands, LXVI. Synthesis, Characterization, and Variable-Temperature 1H- and 19F-NMR Investigations of Cerium(IV) Double-Deckers Derived from Monofunctionalized Tetraarylporphyrins

Johann W. Buchler; Volker Eiermann; Helmut Hanssum; Georg Heinz; Heinz Rüterjans; Markus Schwarzkopf

Archive | 2001

Pharmaceutical formulation containing thienopyrimidines and antithrombotics, calcium antagonists, prostaglandins or prostaglandin derivatives (2)

Hans-Michael Eggenweiler; Volker Eiermann

Archive | 2002

PHARMACEUTICAL FORMULATION COMPRISING PYRAZOLO[4,3-d]PYRIMIDINES AND ENDOTHELIN RECEPTOR ANTAGONISTS OR THIENOPYRIMIDINES AND ENDOTHELIN RECEPTOR ANTAGONISTS

Hans-Michael Eggenweiler; Volker Eiermann; Pierre Schelling

Archive | 2001

Pharmaceutical formulation comprising pyrazolo[4,3-d]pyrimidine and nitrates or thienopyrimidines and nitrates

Hans-Michael Eggenweiler; Volker Eiermann; Pierre Schelling

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Hans-Michael Eggenweiler

Merck

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Gerhard Barnickel

Merck

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Christoph Seyfried

Merck

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Pierre Schelling

Medical College of Wisconsin

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Rolf Gericke

Merck

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Amsterdam Christoph Van

Merck

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Hans-Eckart Radunz

Merck

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Wilfried Rautenberg

Merck

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Gerd Bartoszyk

Merck KGaA

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Hans-Michael Eggenweiler

Merck

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