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Warren M. Zapol

CARE

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Publication

Featured researches published by Warren M. Zapol.

BMC Pharmacology | 2007

Therapeutic potential of soluble guanylate cyclase agonists in pulmonary hypertension

Oleg V. Evgenov; Daniel S. Kohane; Warren M. Zapol

Pharmacological, NO-independent sGC agonists have been evaluated in several models of PH. Intravenous administration of the sGC stimulator BAY 41–2272 attenuates pulmonary vasoconstriction in ovine models of acute chemically-induced PH and persistent PH of the newborn. In rodent models of hypoxiaor monocrotaline-induced PH, oral treatment or intramuscular injections of BAY 41–2272 or oral administration of the sGC activator BAY 58–2667 attenuates the increase of right ventricular systolic pressure, right ventricular hypertrophy, and structural remodeling of the lung vasculature.

Archive | 2007

Attenuation of vasoactive oxygen carrier-induced vasoconstriction

Warren M. Zapol; Binglan Yu; Fumito Ichinose

Archive | 2005

Enhancing the effectiveness of an inhaled therapeutic gas

Kenneth D. Bloch; Fumito Ichinose; Warren M. Zapol; Oleg V. Evgenov

Archive | 2015

HETEROARYL DISULFIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR INCREASING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN

Warren M. Zapol; Kenneth D. Bloch; Akito Nakagawa; Francine E. Lui; Revital Freedman

Archive | 2015

aerosols in acute pulmonary hypertension Pulmonary vasodilation by nitric oxide gas and prodrug

Warren M. Zapol; Christophe Adrie; Fumito Ichinose; Alexandra Holzmann; Larry K. Keefer; E William

Archive | 2015

during one-lung ventilation in mice vasoconstriction and enhances systemic oxygenation NOS3 deficiency augments hypoxic pulmonary

Rong Liu; Oleg V. Evgenov; Fumito Ichinose; Donald B. Bloch; Warren M. Zapol; Norbert Weissmann; J. T. Sylvester; Larissa A. Shimoda; Philip I. Aaronson; Jeremy P. T. Ward

Archive | 2015

activation and subsequent RhoA activation barrier dysfunction involves Smad2-dependent p38

Sharon Rounds; Qing Lu; Elizabeth O. Harrington; Heather Jackson; Nicole A. Morin; Am J; Craig Kent; Pasithorn A. Suwanabol; Stephen Seedial; Fan Zhang; Xudong Shi; Bo Liu; Dimitrios Georgopoulos; Warren M. Zapol; Kenneth D. Bloch; Eleni Vergadi; Evangelos Kaniaris; Maria Hatziapostolou; Eleni Lagoudaki

Archive | 2015

BISAMIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR REDUCING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN

Warren M. Zapol; Kenneth D. Bloch; Akito Nakagawa; Francine E. Lui; Revital Freedman

Archive | 2010

Nitric Oxide and Inhaled Pulmonary Vasodilators

Fumito Ichinose; Warren M. Zapol

Archive | 2007

Nitric oxide delivery device

Warren M. Zapol; Binglan Yu; Fumito Ichinose

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Collaboration

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Fumito Ichinose

Harvard University

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Kenneth D. Bloch

Harvard University

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Binglan Yu

Harvard University

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Oleg V. Evgenov

CARE

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Akito Nakagawa

Osaka University

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Francine E. Lui

University of Toronto

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Alexandra Holzmann

Heidelberg University

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Bo Liu

Cornell University

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Craig Kent

University of Wisconsin-Madison

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Daniel S. Kohane

Boston Children's Hospital

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