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Wen-Lin Kuo

University of California, San Francisco

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Featured researches published by Wen-Lin Kuo.

Genomics | 1992

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

M.-C. Potier; Wen-Lin Kuo; A. Dutriaux; Joe W. Gray; Michel Goedert

A library of yeast artificial chromosomes (YACs) was constructed from a human/hamster somatic cell hybrid containing human chromosome 21 (q11-qter). Cells were embedded in agarose, and the DNA was partially digested with EcoRI, released into solution by agarase treatment of the agarose plugs, ligated into pYAC4, and transferred into yeast. Double screening of the yeast transformants with human and hamster genomic DNA allowed the selection of clones hybridizing only with human DNA. The library consists of 321 clones, amounting to 1.5 equivalents (61 Mb) of chromosome 21. The mean YAC size calculated from 178 clones is 190 +/- 100 kb. Screening of the library with eight sequence-tagged sites gave six positives. Among 21 YACs tested by in situ hybridization, 17 mapped to chromosome 21.

Cancer Research | 1998

The Human Homologue for the Caenorhabditis elegans cul-4 Gene Is Amplified and Overexpressed in Primary Breast Cancers

Ling-Chun Chen; Sharmila Manjeshwar; You Lu; Dan H. Moore; Britt-Marie Ljung; Wen-Lin Kuo; Shanaz H. Dairkee; Meredith Wernick; Colin Collins; Helene S. Smith

Genomics | 1996

cDNA cloning and gene structure of a novel water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13.

Tonghui Ma; Baoxue Yang; Wen-Lin Kuo; A. S. Verkman

Cancer Research | 1994

A Candidate Tumor Suppressor Gene in Human Breast Cancers

David R. Schott; Julielani Ngo Chang; Guoren Deng; Wayne Kurisu; Wen-Lin Kuo; Joe W. Gray; Helene S. Smith

Genomics | 1997

Assignment of HMAT1, the human homolog of the murine mammary transforming gene (MAT1) associated with tumorigenesis, to 1q21.1, a region frequently gained in human breast cancers.

Soo-In Hwang; Wen-Lin Kuo; Joanne F. Cochran; Raphael C. Guzman; Tetsuya Tsukamoto; Gautam K. Bandyopadhyay; Ken Myambo; Colin Collins

Genomics | 1997

Mapping of a newly discovered human gene homologous to the apoptosis associated-murine mammary protein, MFG-E8, to chromosome 15q25.

Colin Collins; Jan O. Nehlin; John D. Stubbs; David Kowbel; Wen-Lin Kuo; Gordon Parry

Archive | 2002

Methods for diagnosing and monitoring ovarian cancer by screening gene copy numbers

Koei Chin; Wen-Lin Kuo; Daniel Pinkel; Donna G. Albertson; Colin Collins; Joe W. Gray

Archive | 2010

Molecular predictors of biological response to a cenpe inhibitor in cancer

Joe W. Gray; Debopriya Das; Nicholas Wang; Wen-Lin Kuo; Paul T. Spellman; Zhi Hu

Archive | 2002

Methods for diagnosing and monitoring malignancies by screeining gene copy numbers

Wen-Lin Kuo; Daniel Polikoff; Daniel Pinkel; Donna G. Albertson; Andrew Berchuck; Joe W. Gray

Cytogenetic and Genome Research | 1997

Assignment of Protease, Serine-Like 1 (PRSSL1) to human chromosome 19q13 by in situ hybridization and radiation hybrid mapping

Daniel Polikoff; Wen-Lin Kuo; Joanne F. Cochran; M. Wernick; David J. Kowbel; Ken Myambo; Colin Collins

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Joe W. Gray

Oregon Health

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Daniel Pinkel

University of California

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Donna G. Albertson

University of California

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Koei Chin

Oregon Health

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Paul T. Spellman

Lawrence Berkeley National Laboratory

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Anna Lapuk

Lawrence Berkeley National Laboratory

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Britt-Marie Ljung

University of California

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Daniel Polikoff

Lawrence Berkeley National Laboratory

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Frederic Waldman

Quest Diagnostics

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Helene S. Smith

California Pacific Medical Center

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