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Dive into the research topics where Werner Zaugg is active.

Publication


Featured researches published by Werner Zaugg.


Tetrahedron Letters | 2001

New synthesis of oxcarbazepine via remote metalation of protected N-o-tolyl-anthranilamide derivatives

Olivier Lohse; Ulrich Beutler; Peter Fünfschilling; Pascal Furet; Gerhard Penn; Werner Zaugg

Abstract Benzyl and allyl protected N-o-tolyl-anthranilamides were efficiently prepared by Buchwald–Hartwig C–N cross coupling reactions, followed by protection of the amino group. Under directed remote metalation conditions, protected dibenzoazepinones were obtained in good yields. Deprotection of the amine and conversion to an urea furnished a new and efficient synthesis of the antiepileptic drug Trileptal®.


Organic Process Research & Development | 2007

A high-throughput process for valsartan

Ulrich Beutler; Matthias Boehm; Peter Fuenfschilling; Thomas Heinz; Jean-Paul Mutz; Ulrich Onken; Martin Mueller; Werner Zaugg


Archive | 2003

Process for the manufacture of organic compounds

Guang-Pei Chen; Prasad Koteswara Kapa; Eric Loeser; Ulrich Beutler; Werner Zaugg; Michael J. Girgis


Organic Process Research & Development | 2005

A New Industrial Process for Oxcarbazepine

Peter Fuenfschilling; Werner Zaugg; Ulrich Beutler; Daniel Kaufmann; Olivier Lohse; Jean-Paul Mutz; Ulrich Onken; Jean-Louis Reber; David Shenton


Tetrahedron Letters | 2004

A new synthesis of oxcarbazepine using a Friedel–Crafts cyclization strategy

Peter Fünfschilling; Ulrich Beutler; Pascale Hoehn; Olivier Lohse; Werner Zaugg


Archive | 2001

Dibenzo(b,f)azepine derivatives and their preparation

Peter Fünfschilling; Daniel Kaufmann; Olivier Lohse; Ulrich Beutler; Werner Zaugg


Archive | 2001

Dibenzo (b,f) azepine intermediates

Peter Fünfschilling; Olivier Lohse; Ulrich Beutler; Werner Zaugg


Tetrahedron Letters | 2016

Efficient and highly stereoselective assembly of rosuvastatin

Damjan Sterk; Werner Zaugg; Ulrich Beutler; Eric Loeser; Kapa Prasad; Zdenko Casar


Archive | 2009

Dibenzo(b,f)azepine derivatives

Peter Fuenfschilling; Daniel Kaufmann; Olivier Lohse; Ulrich Beutler; Werner Zaugg


Tetrahedron Letters | 2004

Erratum to “A new synthesis of oxcarbazepine using a Friedel–Crafts cyclization strategy” [Tetrahedron Lett. 45 (2004) 5275]

Daniel Kaufmann; Peter Fünfschilling; Ulrich Beutler; Pascale Hoehn; Olivier Lohse; Werner Zaugg

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