Wim Dehaen
Catholic University of Leuven
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Publication
Featured researches published by Wim Dehaen.
Artificial Organs | 2008
Björn Meijers; Viktoria Weber; Bert Bammens; Wim Dehaen; Kristin Verbeke; Dieter Falkenhagen; Pieter Evenepoel
Removal of protein-bound uremic retention solutes, including p-cresol, by peritoneal dialysis and hemodialysis (HD) is limited. p-Cresol, mainly circulating as sulfate conjugate (p-cresyl sulfate [PCS]), is independently associated with mortality. Fractionated plasma separation and adsorption (FPSA) is a nonbiologic detoxification system for the treatment of liver failure. The FPSA clearance of uremic retention solutes is unknown. We studied PCS clearance by FPSA, using the Prometheus system. The neutral resin adsorbent and the anion exchange adsorbent bind PCS in vitro (reduction ratios [RRs] 37 and 70%). Ex vivo, the adsorbent mass removal (MR) (median 47.5 mg) contributes more than half to total MR (median 89.6 mg). In vivo, PCS RR during FPSA (50%) exceeded the RR during high flux HD (30%). We halted the study after four inclusions due to repeated thrombosis of the arterio-venous conduit. In conclusion, FPSA is a promising technique to improve clearance of protein-bound uremic retention solutes.
Macromolecular Chemistry and Physics | 2001
Guennady Evmenenko; Barry J. Bauer; Ralf Kleppinger; Bart Forier; Wim Dehaen; Eric J. Amis; Nikolai Mischenko; Harry Reynaers
The size of poly(benzyl ether) dendrimers with different molecular architectures was measured by small angle neutron scattering (SANS). Both polar and non-polar solvents were used to measure the effect of solvent type. The radius of gyration (Rg) of all of the dendrimers follows a scaling law of Rg M1/3 consistent with literature values of other chemically different dendrimers. The effect of solvent type on dendrimer size was minimal.
Physica B-condensed Matter | 2000
Guennadi Evmenenko; Barry J. Bauer; N Mischenko; B Forier; Wim Dehaen; R Kleppinger; Eric J. Amis; H Reynaers
Abstract The analysis of SANS data for a series of the poly(benzyl ether) dendrimers of different molecular architecture in deuterated tetrahydrofuran and toluene allowed to obtain information about some regularities of the relation between the topology of the dendrimer molecule and its structural parameters. The dimension of the present dendrimers of the poly(benzyl ether) type points to a scaling law of the type R g ∼ M 1/3 in line with literature information obtained for other chemically different dendrimers.
Archive | 2010
Joice Thomas; Wouter Maes; Koen Robeyns; Margriet Ovaere; L. Van Meervelt; Mario Smet; Wim Dehaen
Related Article: J.Thomas, W.Maes, K.Robeyns, M.Ovaere, L.Van Meervelt, M.Smet, W.Dehaen|2009|Org.Lett.|11|3040|doi:10.1021/ol901044m
Zeitschrift Fur Kristallographie-new Crystal Structures | 2003
Koen Uytterhoeven; L. Van Meervelt; Mario Smet; Wim Dehaen
Abstract C41H33NO6, triclinic, P1̅ (No. 2), a = 9.610(3) Å, b = 12.877(3) Å, c = 15.138(4) Å, α = 109.29(2)°, β = 105.16(2)°, γ = 94.24(2)°, V = 1680.0 Å3, Z = 2, Rgt(F) = 0.059, wRref(F2) = 0.161, T = 289 K.
Tetrahedron | 2005
Nadya Kaval; Beáta Halász-Dajka; Giang Vo-Thanh; Wim Dehaen; Johan Van der Eycken; Péter Mátyus; André Loupy; Erik Van der Eycken
Archive | 2004
Vasiliy A. Bakulev; Wim Dehaen
Steviol glycosides: technical and pharmacological aspects | 2008
Tom Struyf; Nancy Paola Chandia Parra; Wim De Borggraeve; Wim Dehaen; Jan Geuns
Mendeleev Communications | 2002
Natalya N. Volkova; Evgeniy V. Tarasov; M. I. Kodess; Wim Dehaen; Vasiliy A. Bakulev
Archive | 2000
Wim Dehaen; Marieke Voets; Vasiliy A. Bakulev