Wing-Wah Sy

Nitration of substituted styrenes with nitryl iodide

Abstract Nitration of substituted styrenes by nitryl iodide, followed by treatment of the product with triethylamine, gives β-nitrostyrenes in good yield.

IODINATION OF AROMATIC AMINES WITH IODINE AND SILVER SULFATE

Abstract Iodination of aromatic amines with iodine / silver sulfate at room temperature gives iodo-products in good (46-96%) yield.

Aromatic Iodination with Iodine and Silver Sulfate

Abstract Iodination of alkyl and alkoxybenzenes with iodine and silver sulfate at room temperature gives iodinated aryl compounds in good yield.

Iodination of alkylbenzenes with iodine and silver nitrite

Abstract Iodination of alkylbenzenes with iodine and silver nitrite at room temperature gives iodoalkylbenzenes in good yield.

Iodination with Silver Sulfate and Iodine. II. Uridines

Abstract Iodination of uridines with iodine and silver sulfate at room temperature gives iodinated uridines in excellent yield.

Deacetylated ketoconazole: A major ketoconazole metabolite isolated from mouse liver

This paper describes the isolation and characterization of a novel metabolite of ketoconazole from hepatic tissue following a treatment regimen associated with ketoconazole induced phospholipidosis

Synthesis and Spectral Properties of 2,5-Dimethoxy-4-Ethoxyamphetamine and Its Precursors

2,5-Dimethoxy-4-ethoxyamphetamine (MEM) was synthesized by two routes. The gas liquid chromatographic data and ultraviolet, infrared, proton magnetic resonance, carbon-13 magnetic resonance, and mass spectra are presented for this amphetamine as well as its precursors. This amphetamine was found to be identical to the sample submitted by the police.

A Direct Synthesis of O6-Monoacetylmorphine from Morphine

ABSTRACTO6-Monoacetylmorphine was synthesized directly in good yield from morphine with glacial acetic acid using sulphuric acid as a catalyst. The product was characterized by PMR, IR, MS, and elemental microanalysis. This successful synthesis of O6-monoacetylmorphine from morphine shows that this compound can be included under the Narcotic Control Act as a regulated substance for legal purposes.

CHEMICAL AND PHYSICAL PROPERTIES OF (Z)—AND (E) -MONOETHOXY-1-(2-NITRO-1-PROPENYL) BENZENES: Important Precursors to the monoethoxyamphetamines

ABSTRACT(Z)-Monoethoxy-1- (2-nitro-1-propenyl)benzenes were synthesized from the corresponding (E)-isomers by irradiation with light in toluene in the presence of benzophenone. The gas-liquid chromatographic (GLC) and thin-layer chromatographic (TLC) data, and ultraviolet (UV), infrared (IR), proton magnetic resonance (1H-NMR), and mass spectra (MS) are presented for both isomers for comparison. The (Z)-isomer is partially converted on the injector of GLC apparatus to the (E)-isomer.

Characterization of Cis-Cinnamoylcocaine

ABSTRACTThe physical properties of highly purified cis-cinnamoylcocaine are reported, including the proton and carbon NMR, IR, UV and mass spectra; the melting point is 72–73°. Details of the chromatographic purification are also given.