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Dive into the research topics where Wouter F. van Leeuwen is active.

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Featured researches published by Wouter F. van Leeuwen.


Journal of Hand Surgery (European Volume) | 2016

Negative Ulnar Variance and Kienböck Disease.

Wouter F. van Leeuwen; Kamilcan Oflazoglu; Mariano E. Menendez; David Ring

PURPOSE To test the primary null hypothesis that there is no difference in mean ulnar variance (UV) scaled to the length of the capitates between 166 wrists with Kienböck disease and an equal number of matched controls and to test the secondary null hypothesis that mean scaled UV does not vary based on age, sex, or race in both Kienböck and control wrists. METHODS Ulnar variance was measured on posteroanterior radiographs of the wrist as the distance between a line through the midpoint between the volar and the dorsal edges of the ulnar margin of the radius and a line tangential to the most distal aspect of the carpal surface of the head of the ulna, both perpendicular to the longitudinal axis of the radius. Measurement of UV was scaled to the length of the capitate, resulting in a UV to capitate height (UV:CH) ratio. RESULTS We found a significant difference in mean UV:CH ratio between patients with Kienböck disease and a control group matched by age, sex, race, and limb. The prevalence of negative UV was high in both patients with Kienböck disease and matched controls. There were no differences in mean UV:CH ratio with respect to age, sex, or race among patients with Kienböck disease or matched controls. CONCLUSIONS The precise role of ulna minus in the development of Kienböck disease remains uncertain and unanswered, given that many patients with Kienböck disease have neutral or positive UV. In addition, a large proportion of the normal population has negative UV, whereas Kienböck disease is rare.


Clinical Orthopaedics and Related Research | 2016

What Is the Radiographic Prevalence of Incidental Kienböck Disease

Wouter F. van Leeuwen; Stein J. Janssen; Dirk P. ter Meulen; David Ring

BackgroundKienböck disease is characterized by osteonecrosis of the lunate. Not all patients with radiographic evidence of the disease experience symptoms bothersome enough to consult a doctor. Little research has been performed on the prevalence of Kienböck disease, and the prevalence in the asymptomatic population is unclear. Knowledge of the natural course of the disease and how often patients are not bothered by the symptoms is important, because it might influence the decision as to whether disease-modifying treatment would be beneficial.Questions/purposes(1) What is the prevalence of incidental and symptomatic Kienböck disease? (2) What are the factors associated with incidental and symptomatic Kienböck disease? (3) Are there differences in Lichtman stage distribution between incidentally discovered and symptomatic Kienböck disease?MethodsWe retrospectively searched radiology reports of all MRI scans, CT scans, and radiographs that included the wrists of 51,071 patients obtained over an 11-year period at one institution to screen for Kienböck disease and avascular necrosis of the lunate. Corresponding MR images, CT scans, or radiographs were reviewed by an orthopaedic hand surgeon to confirm the presence of Kienböck disease when the report was inconclusive. The medical record was reviewed to determine whether the radiographic Kienböck disease was incidental. Prevalences were calculated for both symptomatic and incidental Kienböck disease. Additionally, we assessed the association of age, sex, and race with incidental and symptomatic Kienböck disease as well as the radiographic severity according to the Lichtman classification and calculated odds ratios.ResultsWe identified 51 cases (0.10%) of incidental Kienböck disease and 87 cases (0.17%) of symptomatic Kienböck disease out of 51,071 patients. Patients with incidental Kienböck were older (mean, 54 years; SD, 17; mean difference, −6.1; 95% confidence interval [CI], −11 to −0.96; p = 0.020) and patients with symptomatic Kienböck disease were younger (mean, 43 years; SD, 14; mean difference, 5.1; 95% CI, 1.2–9.0; p = 0.010) compared with the group of patients without Kienböck disease (mean, 48 years; SD, 19). Lunate collapse (Lichtman Stages III and IV) was seen in nine of 51 patients (18%) with incidental Kienböck disease and in 44 of 87 patients (51%) with symptomatic Kienböck disease (odds ratio, 0.21; 95% CI, 0.086–0.51; p < 0.001). Our study did not identify any other factors associated with Kienböck disease.ConclusionsWe found that Kienböck disease is diagnosed on radiographs in a notable number of asymptomatic patients and that asymptomatic patients are more likely to have precollapse stages of the disease. This suggests that symptoms and disability do not correlate with pathophysiology, progression, or activity. Patients and surgeons benefit from awareness that symptoms are not a good indicator of the severity or prognosis of pathophysiology and that lunate osteonecrosis can exist with no or insufficient symptoms. This is important when considering treatment, because we cannot distinguish active disease at risk of collapse that could merit disease-modifying treatment from disease that will not progress.Level of EvidenceLevel III, prognostic study.


American Journal of Sports Medicine | 2016

The J-Shaped Bone Graft for Anatomic Glenoid Reconstruction A 10-Year Clinical Follow-up and Computed Tomography–Osteoabsorptiometry Study

Christian Deml; Peter Kaiser; Wouter F. van Leeuwen; Magdalena Zitterl; Simon A. Euler

Background: The J-shaped bone graft procedure is one of the recommended methods to reconstruct significant glenoid rim defects. Purpose: To evaluate long-term (minimum 10-year) clinical outcomes and show further details of the remodeling effects on the articular cavity of the glenoid after J-shaped bone grafting. Study Design: Case series; Level of evidence, 4. Methods: A total of 14 patients treated with a J-shaped bone graft procedure were observed clinically. Additionally, bilateral preoperative and postoperative follow-up computed tomography (CT) scans were used for CT-osteoabsorptiometry (OAM) to evaluate the bony remodeling processes. Results: The follow-up rate was 93% at a mean follow-up time of 10.7 years (range, 10.08-11.75 years). Patients exhibited a mean Constant score of 92.5 (range, 80-100) on the clinical evaluation. All patients had free range of motion and were pain free without any recurrence of instability. Based on CT-OAM, comparable and almost anatomically reconstructed, bilaterally equal glenoid cavities were found postoperatively. The distribution patterns of glenoid subchondral mineralization were bilaterally equal in 85.7% of the patients. Conclusion: The surgical treatment of recurrent shoulder instability with a significant bony Bankart lesion using the J-shaped bone graft procedure provided excellent long-term results. This study lends evidence to support the capability of the J-shaped bone graft procedure to restore the normal glenoid shape due to physiological remodeling processes.


Journal of Hand Surgery (European Volume) | 2016

Radiographic Progression of Kienböck Disease: Radial Shortening Versus No Surgery

Wouter F. van Leeuwen; Stein J. Janssen; David Ring

PURPOSE The natural course of the pathophysiology of Kienböck disease is uncertain. Shortening of the radius is believed to modify the pathophysiology by addressing mechanical influences on the lunate. The aim of this study was to compare the radiographic progression of Kienböck disease among patients who had radial shortening osteotomy and patients who had no surgical treatment, with a minimum 1-year interval between radiographs. METHODS Among 207 patients with Kienböck disease, we included all 48 eligible patients who had either radial shortening osteotomy or nonsurgical treatment and 2 sets of wrist radiographs available a minimum of 1 year apart. We compared changes in carpal height ratio, Stahl index, and carpal angles between the 2 sets of radiographs and between radial shortening osteotomy and nonsurgical treatment. RESULTS We found, on average, a small decrease in the carpal height ratio and the Stahl index in patients who did and did not have surgery, with no differences between the 2 groups. Nearly half of the patients had no decrease in the carpal height ratio and/or the Stahl index. CONCLUSIONS Radiographic progression of Kienböck over 1 year or more seems slight on average regardless of treatment. Future research might address the probability of and factors associated with radiographic progression of Kienböck disease. TYPE OF STUDY/LEVEL OF EVIDENCE Prognostic IV.


Injury-international Journal of The Care of The Injured | 2016

Does perceived injustice correlate with pain intensity and disability in orthopaedic trauma patients

Wouter F. van Leeuwen; Quirine M.J. van der Vliet; Stein J. Janssen; Marilyn Heng; David Ring; Ana-Maria Vranceanu

INTRODUCTION Individuals who experience musculoskeletal trauma may construe the experience as unjust and themselves as victims. Perceived injustice is a cognitive construct comprised by negative appraisals of the severity of loss as a consequence of injury, blame, injury-related loss, and unfairness. It has been associated with worse physical and psychological outcomes in the context of chronic health conditions. The purpose of this study is to explore the association of perceived injustice to pain intensity and physical function in patients with orthopaedic trauma. METHODS A total of 124 orthopaedic trauma patients completed the Injustice Experience Questionnaire (IEQ), the PROMIS Physical Function Computer Adaptive Testing (CAT), the PROMIS Pain Intensity instruments, the short form Patient Health Questionnaire for depression (PHQ-2), the short form Pain Self-Efficacy Questionnaire (PSEQ-2), and the short form Pain Catastrophizing Scale (PCS-4) on a tablet computer. A stepwise linear regression model was used to identify the best combination of predictors explaining variance in PROMIS Physical Function and PROMIS Pain Intensity. RESULTS The IEQ was associated with PROMIS Physical Function (r=-0.36; P<0.001) and PROMIS Pain Intensity (r=0.43; P<0.001). In multivariable analysis, however, Caucasian race (β=5.1, SE: 2.0, P=0.013, 95% CI: 1.1-9.2), employed work status (β=5.1, SE: 1.5, P=0.001, 95% CI: 2.1-8.2), any cause of injury other than sports, mvc, or fall (β=7.7, SE: 2.1, P<0.001, 95% CI: 3.5-12), and higher self-efficacy (PSEQ-2; β=0.93, SE: 0.23, P<0.001, 95% CI: 0.48-1.4) were selected as part of the best model predicting variance in PROMIS Physical Function. Only a higher degree of catastrophic thinking (PCS-4; β=1.2, SE: 0.12, P<0.001, 95% CI: 0.99 to 1.5) was selected as important in predicting higher PROMIS Pain Intensity. CONCLUSION Perceived injustice was associated with both physical function and pain intensity in bivariate correlations, but was not deemed as an important predictor when assessed along with other demographic and psychosocial variables in multivariable analysis. This study confirms prior research on the pivotal role of catastrophic thinking and self-efficacy in reports of pain intensity and physical function in patients with acute traumatic musculoskeletal pain.


Clinical Orthopaedics and Related Research | 2016

What Factors are Associated With a Surgical Site Infection After Operative Treatment of an Elbow Fracture

Femke M.A.P. Claessen; Yvonne Braun; Wouter F. van Leeuwen; George S.M. Dyer; Michel P. J. van den Bekerom; David Ring

BackgroundSurgical site infections are one of the more common major complications of elbow fracture surgery and can contribute to other adverse outcomes, prolonged hospital stays, and increased healthcare costs.Questions/purposesWe asked: (1) What are the factors associated with a surgical site infection after elbow fracture surgery? (2) When taking the subset of closed elbow fractures only, what are the factors associated with a surgical site infection? (3) What are the common organisms isolated from an elbow infection after open treatment?MethodsOne thousand three hundred twenty adult patients underwent surgery for an elbow fracture between January 2002 and July 2014 and were included in our study. Forty-eight of 1320 patients (4%) had a surgical site infection develop. Thirty-four of 1113 patients with a closed fracture (3%) had a surgical site infection develop.ResultsFor all elbow fractures, use of plate and screw fixation (adjusted odds ratio [OR]= 2.2; 95% CI, 1.0–4.5; p = 0.041) and use of external fixation before surgery (adjusted OR = 4.7; 95% CI, 1.1–21; p = 0.035) were associated with higher infection rates. When subset analysis was performed for closed fractures, only smoking (adjusted OR = 2.2; 95% CI, 1.1–4.5; p = 0.023) was associated with higher infection rates. Staphylococcus aureus was the most common bacteria cultured (59%).ConclusionsThe only modifiable risk factor for a surgical site infection after open reduction and internal fixation was cigarette smoking. Plate fixation and temporary external fixation are likely surrogates for more complex injuries, therefore no recommendations should be inferred from this association. Surgeons should counsel patients who smoke.Level of EvidenceLevel IV, prognostic study.


Journal of Shoulder and Elbow Surgery | 2017

Risk factors for reoperation after total elbow arthroplasty

Donato Perretta; Wouter F. van Leeuwen; George S.M. Dyer; David Ring; Neal C. Chen

BACKGROUND Total elbow arthroplasty (TEA) is a treatment option for arthritic conditions of the elbow and for complex distal humerus fractures in the elderly. Complications are common, however, and rates of survivorship vary. The goal of this study was to describe the factors associated with reoperation and revision after TEA. METHODS We retrospectively reviewed primary TEAs performed at 2 tertiary academic medical centers. We identified 102 primary TEAs in 82 patients by 9 surgeons. The average age of the patients was 61 years. Female patients represented 81% of TEAs performed. The mean follow-up was 6.1 years. The principal diagnosis was inflammatory arthritis in 63 patients (62%), acute trauma or post-trauma in 28 (27%), and primary osteoarthritis in 9 (8.8%). RESULTS The rate of reoperation was 41% (42 of 102). The median time to the first reoperation was 1.8 years. The percentage of elbows that had 1 or both components revised was 30% (31 of 102). The most common indication for reoperation was component loosening (17). Six elbows were treated definitively with resection arthroplasty, and 1 was revised to an elbow fusion. The rate of implant revision was 27% for inflammatory arthritis, 11% for osteoarthritis, and 57% after trauma. Trauma-related TEA was more likely to undergo additional reoperation (odds ratio, 4.3; P = .008) and implant revision (odds ratio, 3.4; P = .031). CONCLUSION Revision surgery with implant revision after primary TEA is common. Trauma-related TEA often leads to additional procedures.


Journal of Hand Surgery (European Volume) | 2017

Carpal Coalitions on Radiographs: Prevalence and Association With Ordering Indication

Bastiaan T. van Hoorn; Taylor Pong; Wouter F. van Leeuwen; David Ring

PURPOSE Carpal coalitions are common and usually incidental to the indication for wrist radiographs. It is not clear if, or when, carpal coalitions cause pain. The aim of this study was to assess the prevalence of incidental carpal coalitions by evaluating radiographs taken for various indications and to test the association of demographic variables and ordering indications with the finding of a carpal coalition. METHODS We reviewed 1,119 posteroanterior wrist radiographs for the presence of carpal coalition. We used bivariate and multivariate analyses to assess demographic factors for their independent associations with the presence of carpal coalitions and to compare the difference in the prevalence of carpal coalitions between radiographs obtained to evaluate traumatic wrist pain (623 wrists), nontraumatic wrist pain (175 wrists), and other reasons (321 wrists). RESULTS Radiographs of 98 out of 1,119 patients (8.8%) showed a carpal coalition. Carpal coalitions were equally likely on radiographs obtained for traumatic wrist pain and nontraumatic wrist pain. Patients with no wrist trauma or wrist pain were less likely to have a carpal coalition on their radiograph. CONCLUSIONS We consider carpal coalitions an unlikely cause of wrist pain. The lower prevalence in radiographs obtained for causes other than wrist trauma or wrist pain remains unexplained, although it may be spurious. In the evaluation of a patient with nonspecific wrist pain, clinicians should be careful ascribing symptoms to anatomical variations on radiographs. These incidental findings should not usually affect management. TYPE OF STUDY/LEVEL OF EVIDENCE Diagnostic III.


Journal of Shoulder and Elbow Surgery | 2016

Incidental magnetic resonance imaging signal changes in the extensor carpi radialis brevis origin are more common with age.

Wouter F. van Leeuwen; Stein J. Janssen; David Ring; Neal C. Chen

BACKGROUND Patients with enthesopathy of the extensor carpi radialis brevis (ECRB) demonstrate signal changes on magnetic resonance imaging (MRI). It is likely that these MRI changes persist for many years or may be permanent, regardless of symptoms, and represent an estimation of disease prevalence. We tested the hypothesis that the prevalence of incidental signal changes in the ECRB origin increases with age. METHODS We searched MRI reports of 3374 patients who underwent an MRI scan, including the elbow, for signal changes in the ECRB origin. Medical records were reviewed for symptoms consistent with ECRB enthesopathy. Prevalences of incidental and symptomatic signal changes were calculated and stratified by age. We used multivariate logistic regression analysis to test whether age, sex, and race were independently associated with ECRB enthesopathy and calculated odds ratios. RESULTS Signal changes in ECRB origin were identified on MRI scans of 369 of 3374 patients (11%) without a clinical suspicion of tennis elbow. The prevalence increased from 5.7% in patients aged between 18 and 30 years up to 16% in patients aged 71 years and older. Older age (odds ratio, 1.04; P <.001) was independently associated with the incidental finding of ECRB enthesopathy on elbow MRI scans. CONCLUSIONS Increased MRI signal in the ECRB origin is common in symptomatic and in asymptomatic elbows. Our findings support the concept that ECRB enthesopathy is a highly prevalent, self-limited process that seems to affect a minimum of 1 in approximately every 7 people.


Journal of wrist surgery | 2018

Variation in Repair of the Triangular Fibrocartilage Complex

Thomas J.M. Kootstra; Wouter F. van Leeuwen; Neal C. Chen; David Ring

Background There is controversy regarding the value of repair of the triangular fibrocartilage complex (TFCC). Given that an acute tear of the TFCC associated with a displaced distal radius fracture uncommonly benefits from repair, the role of repair in other settings is uncertain. Our impression is that TFCC repair is highly variable from surgeon‐to‐surgeon. Purpose The purpose of this study is to determine the rate of TFCC repair in patients who had a magnetic resonance imaging (MRI) scan of the wrist obtained for ulnar‐sided wrist pain, and that showed signal changes in the TFCC. We tested the primary null hypothesis that there are no demographic or surgeon factors associated with repair of the TFCC. Patients and Methods Three hundred and ninety‐four patients with ulnar‐sided wrist pain and an MRI scan showing changes in the TFCC were included in this retrospective study. No patients had instability of the distal radioulnar joint (DRUJ) recorded in the medical record. Surgical repair of TFCC tears was used as the primary outcome during statistical analysis to identify factors associated with repair. Results Out of 394 (6%), 25 patients underwent TFCC repair. We found that 10% of the treating surgeons (4 out of 41) performed 80% of the procedures (20 out of 25). Patients who discerned a trauma prior to their symptoms and patients whose MRI showed signal changes primarily in the ulnar portion of the TFCC were more likely to have surgical repair. Conclusion We found that the rate of TFCC repair varies substantially from surgeon‐to‐surgeon. The observation that repair is more likely to happen when patients perceive themselves as injured suggests that perception of injury affects how patients and surgeons consider treatment options. To help avoid surgeries based on surgeon bias or patient misperception, we suggest studying the effect of tools that provide simple, balanced, dispassionate, and empowering information (e.g., decision aids) that can limit surgeon‐to‐surgeon variation. Level of Evidence Level IV.

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David Ring

University of Texas at Austin

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George S.M. Dyer

Brigham and Women's Hospital

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Simon A. Euler

Innsbruck Medical University

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A. Lee Osterman

Thomas Jefferson University

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