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Tetrahedron Letters | 1996

Practical enantiospecific synthesis of RPR 111905: A novel non-peptide substance P antagonist

Stephane Mutti; Christophe Daubie; Joel Malpart; Xavier Radisson

Abstract The synthesis of enantiomerically pure RPR 111905 was achieved in twelve steps with an overall yield of 6.9%. The synthetic strategy was based on a Diels-Alder reaction to generate the bicyclic framework and the asymmetry was introduced by resolution.


Archive | 1991

Process for the preparation of derivatives of 3,5-dihydroxypentanoic acid

Patrick Leon; Xavier Radisson; Viviane Massonneau


Archive | 1994

Pristinaymcinia or virginiamycin derivatives and their preparation

Jean-Pierre Bastart; Jean-Marc Paris; Xavier Radisson


Archive | 1991

Salts derived from 26-(dialkylaminoalkylsulphonyl)pristinamycin IIB

Jean-Claude Barriere; Jean-Pierre Corbet; Jean-Marc Paris; Xavier Radisson


Archive | 1991

PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3,5-DIHYDROXY PENTANOIC ACID.

Patrick Leon; Viviane Massoneau; Xavier Radisson


Archive | 1991

Process for the preparation of 3,5-dihydroxy 6-oxo hexanoic acid

Patrick Leon; Viviane Massonneau; Xavier Radisson


Archive | 1994

Process for the preparation of difunctional compounds of high enantiomeric purity

Xavier Radisson


Archive | 1992

PROCEDE DE PREPARATION DE DERIVES DU TETRAHYDROPYRANNE.

Patrick Leon; Viviane Massonneau; Xavier Radisson


Archive | 1992

Chiral sulfates, their preparation and their use for the synthesis of pharmaceutical products.

Xavier Radisson


Archive | 1994

METHOD FOR PREPARING DIFUNCTIONAL COMPOUNDS HAVING HIGH ENANTIOMERIC PURITY

Xavier Radisson

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