Xi Tang

Analysis of 16 phthalic acid esters in food simulants from plastic food contact materials by LC‐ESI‐MS/MS

An RP LC-ESI-MS/MS method for the determination of the migration of 16 primary phthalic acid esters from plastic samples has been developed using distilled water, 3% acetic acid, 10% alcohol, and olive oil as food simulants. Detection limits were 1.6-18.5 μg/kg in distilled water, 1.4-17.3 μg/kg in 3% acetic acid, 1.4-19.2 μg/kg in 10% alcohol, and 31.9-390.8 μg/kg in olive oil. The RSDs were in the range of 0.07-11.28%. The real plastic products inspection showed that only few analyzed samples were phthalates contaminated. Bis-2-ethylhexyl ester and dibutyl phthalate were the common items migrated from the plastic products into food and feeds, but the migration concentrations were far below the limits set by European Union (1.5 mg/kg for bis-2-ethylhexyl ester and 0.3 mg/kg for dibutyl phthalate).

Determination of the migration of eight parabens from antibacterial plastic packaging by liquid chromatography-electrospray ionization-tandem mass spectrometry

A method based on reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS) coupled with solid phase extraction (SPE) was developed and validated for qualitative and quantitative detection of eight parabens in four types of food simulant sample, including distilled water, 3% acetic acid, 10% ethanol and olive oil. The detection limits of the eight parabens after the SPE procedure were in the range of 0.005–0.010 μg L−1 in distilled water, 0.006–0.015 μg L−1 in 3% acetic acid, 0.005–0.017 μg L−1 in 10% ethanol and 0.2–0.6 μg L−1 in olive oil. The relative standard deviations (RSDs) were in the range of 1.90–8.48% for distilled water, 1.01–3.73% for 3% acetic acid, 5.78–12.97% for 10% ethanol and 0.29–5.40% for olive oil. The proposed method was applied to assess the migration of parabens from real antibacterial plastic packaging samples with satisfactory results.

Determination of Eight Parabens in Water-Based Food Simulants Migrated from Antibacterial Plastic Packaging by LC/MS/MS

A method based on reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS) combined with solid phase extraction (SPE) was developed and validated for qualitative and quantitative detection of eight parabens in three types of water-based food simulants including distilled water, 3% acetic acid, 10% alcohol. Detection limits of eight parabens after SPE procedure were 0.005-0.010 μg/L in distilled water, 0.006-0.015 μg/L in 3% acetic acid and 0.005-0.017 μg/L in 10% alcohol. The relative standard deviations (RSDs) were in the range of 1.90-8.48% for distilled wsater, 1.01-3.73% for 3% acetic acid and 5.78-12.97% for 10% alcohol. The method could make a complement for detecting parabens migrated to food and feeds.