Xiaodong Jin

A red-emitting fluorescent probe based on flavone for hydrazine detection and its application in aqueous solution

On account of the biological harmfulness of hydrazine, we have designed and synthesized a novel red-emitting fluorescent probe (1) based on 3-hydroxyflavone. The probe could selectively and sensitively detect hydrazine over other primary amines, cations and anions. Moreover, we verified the mechanism of probe 1 for detecting hydrazine through a 1H NMR titration and MS spectral analysis. Importantly, the probe could selectively detect hydrazine in different water samples which showed its potential for practical applications.

NIR luminescence for the detection of latent fingerprints based on ESIPT and AIE processes

In this paper, a facile near infrared (NIR, 650–900 nm) probe 4-dimethylamino-2′-hydroxychalcone (NIR-LP) based on the excited state intramolecular proton transfer (ESIPT) – aggregation induced emission (AIE) processes for the detection of the latent fingerprints (LFPs) was developed for the first time. The probe can distinguish the fresh LFPs, but also recognize the aged (10 days) LFPs.

Aza-boron-diquinomethene complexes bearing N-aryl chromophores: synthesis, crystal structures, tunable photophysics, the protonation effect and their application as pH sensors

A series of aza-boron-diquinomethene complexes (1a–1e) bearing different N-aryl chromophores were synthesized and characterized by multinuclear NMR spectroscopy, X-ray crystallography, optical absorption and emission spectroscopy, and elemental analysis. These robust thermal complexes possess tunable intense luminescence from blue to red with relatively high emission quantum yields. The introduction of different N-aryl chromophores into the aza-BODIQU core significantly tuned the emission colors. The relationship between their structures and properties was investigated systematically via spectroscopic methods and simulated by density functional theory (DFT) calculations. Additionally, the application of 1c as a pH sensor with a remarkable colour-changing property has been investigated. All these results indicate that these complexes exhibit robust thermal stability, tunable photophysical properties, relatively high photoluminescence quantum yields and protonation effect, making these complexes potential candidates for pH sensors, bioimaging probes and organic light-emitting materials.

Generation of Oxazolidine-2,4-diones Bearing Sulfur-Substituted Quaternary Carbon Atoms by Oxothiolation/Cyclization of Ynamides

A novel method for metal-free oxothiolation of ynamides to construct oxazolidine-2,4-diones bearing sulfur-substituted quaternary carbon atoms has been developed. It represents a rare C-O bond cleavage of ynamides, as well as a facile and tandem approach for the formation of C-O, C-S, and C-Cl bonds. This redox-neutral protocol can be applied to the synthesis of multisubstituted oxazolidine-2,4-diones with good chemoselectivity and good yields of isolated products under mild conditions.

Stereoselective synthesis of (R)-salmeterol via asymmetric cyanohydrin reaction

The authors described a short and highly enantioselective route to (R)-salmeterol involving asymmetric synthesis of cyanohydrin followed by nucleophilic substitution with 6-(4-phenylbutoxy) hexyl methanesulfonate.