Xiyun Zhang
Codexis
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Publication
Featured researches published by Xiyun Zhang.
Journal of Organic Chemistry | 2018
Yong Koy Bong; Shiwei Song; Jovana Nazor; Michael Vogel; Magnus Widegren; Derek Smith; Steven J. Collier; Robert John Wilson; S. M. Palanivel; Karthik Narayanaswamy; Ben Mijts; Michael D. Clay; Ryan Fong; Jeff Colbeck; Amritha Appaswami; Sheela Muley; Jun Zhu; Xiyun Zhang; Jack Liang; David Entwistle
A wild-type Baeyer-Villiger monooxygenase was engineered to overcome numerous liabilities in order to mediate a commercial oxidation of pyrmetazole to esomeprazole, using air as the terminal oxidant in an almost exclusively aqueous reaction matrix. The developed enzyme and process compares favorably to the incumbent Kagan inspired chemocatalytic oxidation, as esomeprazole was isolated in 87% yield, in >99% purity, with an enantiomeric excess of >99%.
Archive | 2010
Behnaz Behrouzian; Robert Mcdaniel; Xiyun Zhang; Louis Clark
Archive | 2010
Jie Yang; Xiyun Zhang; Attila Andor
Archive | 2012
Jie Yang; Xiyun Zhang; Jungjoo Yoon; Kripa Rao; John H. Grate; David Elgart; Dipnath Baidyaroy
Archive | 2010
Xiyun Zhang; Jie Yang; Dipnath Baidyaroy; Sally Rhiannon Postlethwaite; Attila Andor; Louis Clark; Lisa M. Newman
Archive | 2010
Yong Koy Bong; Michael D. Clay; Steven J. Collier; Benjamin Mijts; Michael Vogel; Xiyun Zhang; Jun Zhu; Jovana Nazor; Derek Smith; Shiwei Song
Archive | 2009
Benjamin Mijts; Sheela Muley; Jack Liang; Lisa M. Newman; Xiyun Zhang; James Lalonde; Michael D. Clay; Jun Zhu; John M. Gruber; Jeffrey Colbeck; John D. Munger; Jagadeesh Mavinahalli; Roger Sheldon
Archive | 2013
Xiyun Zhang; Dipnath Baidyaroy
Archive | 2014
Xiyun Zhang; Jie Yang; Dipnath Baidyaroy; Sally Rhiannon Postlethwaite; Attila Andor; Louis Clark; Lisa M. Newman
Archive | 2012
Ee Lui Ang; Ellen Eberhard; Xiyun Zhang; Wei Zhang; Jing Tian; Derek Smith; Vesna Mitchell
