Y.W. Song

Four-Dimensional CT-Based Evaluation of Intrafractional and Interfractional Anastomosis Motion During Postoperative Radiation Therapy in Gastric Cancer: A Prospective Study

greater than the CBCT ITV. It is feasible to generate the 3DCT ITV with an isotropic IM of 5 mm for tumors in the middle-lower lobe. Author Disclosure: F. Li: None. J. Li: None. M. Zhifang: None. Y. Zhang: None. J. Xing: None. Intrafractional motion (mean SD) 2.4 2.3 2.1 2.0 5.6 4.0 Interfractional motion (mean SD) 6.1 6.6 3.3 3.0 4.8 4.3 Intrafractional 95th percentile values 6.8 5.5 13.3 Interfractional 95th percentile values 15.4 10.1 10.7 3674

Toxicity evaluation of capecitabine concurrent chemoradiotherapy for stage II and III rectal cancer

15067 Background: Though preoperative chemoradiotherapy is associated with improved local control and less toxicity compared with postoperative chemoradiotherapy, 5-fluorouracil based postoperative concurrent chemoradiotherapy still remains a more acceptable treatment in China. Efforts are now being focused on developing new cytotoxic agents in combination with radiotherapy (RT) to maintain the treatment results and to decrease the toxicity. A phase II study was conducted to evaluate the acute toxicity and tolerance of capecitabine combination with RT. Methods: Radiotherapy was delivered postoperatively to the total dose of DT 50Gy in 5 weeks to the pelvic region, either in 3-field technique or 3-D conformal therapy. Capecitabine was administered concurrent with RT at a dosage of 1600 mg/m2/d for 2 weeks (1st cycle) followed by a 2nd cycle after a rest of 7 days. Primary endpoint was grade 3 or 4 hematological and non-hematological toxicity. Results: Between March 2005 and December 2006, a total of 75 pat...