Yasuhisa Mineno

Successful Hemostasis after Dental Extraction with the Use of Recombinant Activated Factor VII in a Factor VII Deficient Patient

Abstract We report our experience of successful hemostasis after dental extraction with the use of rF VII a in a FVII deficient patient. Preoperative PT% was 25%, FVII was less than 3%. Thirty minutes before tooth extraction, 1.2 mg of rFVII a was injected. At the beginning of the operation, PT% was more than 200%, FVII was 336%, the hemostasis after dental extraction was excellent. rFVII a was used effectively and safely for dental extraction in this case of FVII deficiency.

Clinical studies on TMJ arthrosis in young people. An epidemiological assessment of TMJ disorder in students by a questionnaire.

In order to do an epidemiological investigation of temporomandibular joint disorder, 612 students of a junior high school and a high school in Nagoya city were investigated by a questionnaire. The results were as follows:1. Frequencies of complaints of temporomandibular joint sound were 12.1%. No significant difference was found in age and sex distributions.(P>0.1)2. 3.7% of junior high school students and 7.9% of high school students complained of more than two complex symptoms (P<0.05), which were typical symptoms of TMJ arthrosis, TMJ sound, pain and limitation.3. For the initial onset of disorder, 55.2% of the total samples indicated that the disorder was manifest in junior high school students. This result suggested the association between complaints of TMJ disorder and dental stage IVA (Hellmans classification).4. The association between complaints of TMJ disorder and feeding, bruxism and chewing on one side were P<0.05 (in girls), P<0.001 (total), P<0.05 (in boys), respectively.5. The results suggested that further extention of the sample is necessary to investigate the etiology of TMJ disorder.