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Featured researches published by Yasuo Tarumoto.


Mutation Research-genetic Toxicology and Environmental Mutagenesis | 1997

Carbon tetrachloride does not induce micronucleus in either mouse bone marrow or peripheral blood

Hiroshi Suzuki; Noriko Hirano; Chiaki Watanabe; Yasuo Tarumoto

We performed mouse bone marrow and peripheral blood micronucleus tests on carbon tetrachloride (CCl4). In the bone marrow assay, bone marrow cells were collected once after 24 h and twice, with a 24-h interval at a dose of 500, 1000 and 2000 mg/kg. In the peripheral blood assay, blood samples were collected 0, 24, 48 and 72 h after a single intraperitoneal injection at a dose of 1000, 2000 and 3000 mg/kg. As a result, micronucleated polychromatic erythrocytes (MNPCEs) were observed neither in the bone marrow assay nor the peripheral blood assay. We concluded that CCl4 does not induce chromosomal aberrations in the mouse bone marrow cells under these experimental conditions.


Journal of Toxicological Sciences | 1981

STUDIES ON TOXICITY OF HYDROCORTISONE 17-BUTYRATE 21- PROPIONATE : 1. Acute Toxicity of Hydrocortisone 17-Butyrate 21-Propionate and Its Analogues in Mice, Rats and Dogs

Yasuo Tarumoto; Satoshi Abe; Yoshifumi Tsutsui; Sadao Nakane; Michitada Sasajima; Masahiro Ohzeki


Journal of Biochemistry | 1981

Effects on Cathepsin B, H, and D in Pectoral Muscle of Dystrophic Chickens (Line 413) of In Vivo Administration of E-64-c (N-[N-(L-3-Transcarboxyoxirane-2-Carbonyl)-L-Leucyl]-3-Methyl-Butylamine)

Takashi Noda; Kazuhide Isogai; Nobuhiko Katunuma; Yasuo Tarumoto; Masahiro Ohzeki


Mutagenesis | 1997

Topoisomerase II inhibitors fail to induce chromosome-type aberrations in etoposide-resistant cells: evidence for essential contribution of the cleavable complex formation to the induction of chromosome-type aberrations

Hiroshi Suzuki; Yasuo Tarumoto; Motoyasu Ohsawa


Muscle & Nerve | 1982

In vivo administration of a thiol protease inhibitor, E-64-C, to hereditary dystrophic chicken

Hideo Sugita; Messrs. Masaaki Kimura; Yasuo Tarumoto; Masaharu Tamai; Kazunori Hanada; Shoichi Ishiura; Ikuya Nonaka; Masahiro Ohzeki; Kazutomo Imahori


Japanese Journal of Pharmacology | 1984

Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats.

Masaaki Kimura; Ryuichi Saziki; Iwao Arai; Yasuo Tarumoto; Sadao Nakane


The Journal of Antibiotics | 1982

Studies on the alpha-glucoside hydrolase inhibitor, adiposin. IV. Effect of adiposin on intestinal digestion of carbohydrates in experimental animals.

Shinjuro Namiki; Kunio Kangouri; Takatoshi Nagate; Hiroshi Hara; Kazuhiko Sugita; Noda K; Yasuo Tarumoto; Sadafumi Omura


Chemical & Pharmaceutical Bulletin | 1989

Studies on topical antiinflammatory agents. I. Synthesis and vasoconstrictive activity of corticosteroid 17-succinyl esters.

Morihiro Mitsukuchi; Jozi Nakagami; Tomoyuki Ikemoto; Shohei Higuchi; Yasuo Tarumoto; Hajime Yasui; Kaoru Sota


Journal of Toxicological Sciences | 1981

[Studies on toxicity of hydrocortisone 17-butyrate 21-propionate -2. Subacute toxicity in rats by subcutaneous administration (author's transl)].

Yasuo Tarumoto; Tokado H; Masaaki Kimura; Kasai A; Iwamatsu Y; Tsuchida T; Noda K; Sadao Nakane; Michitada Sasajima; Masahiro Ohzeki


Journal of Toxicological Sciences | 1981

INFLUENCES OF HYDROCORTISONE 17-BUTYRA-TE 21-PROPIONATE ON THE VISUAL AND THE AUDITORY ORGANS

Takashi Ohshima; Satoshi Abe; Yoshifumi Tsutsui; Takashi Sakagawa; Yasuo Tarumoto; Sadao Nakane; Michitada Sasajima; Masahiro Ohzeki

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Masahiro Ohzeki

Taisho Pharmaceutical Co.

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Masaaki Kimura

Taisho Pharmaceutical Co.

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Sadao Nakane

Taisho Pharmaceutical Co.

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Isamu Nakamura

Taisho Pharmaceutical Co.

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Hajime Yasui

Taisho Pharmaceutical Co.

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Iwao Arai

Taisho Pharmaceutical Co.

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Ryuichi Saziki

Taisho Pharmaceutical Co.

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Shoji Sasaki

Taisho Pharmaceutical Co.

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