Yasushi Murai

2′-C-, 3′-C- and 5′-C-methylsangivamycins: conformational lock with the methyl group

Abstract Introduction of the methyl groups into the appropriate positions of the ribose moiety in sangivamycin (1) induced the deviation of the conformer population which could be predicted by the molecular mechanics calculations.

Synthesis of 4-, 5-, 6- and 7-Substituted N-Tosylindoles from Substituted Anilines

4-, 5-, 6-, and 7-Substituted N-tosylindoles are prepared from N-tosylanilides, carrying 2-acetoxy-1-(isopropylthio)ethyl group at the ortho position, which can be prepared from substituted anilines and dialkyl sulfide by [2,3] sigmatropic rearrangement

Novel 2-methyl-1-oxacephalosporins. II, Synthesis of 3-substituted 2-methyl-1-oxacephem nucleus

The stereoselective syntheses of 3-substituted 2α- and 2β-methyl-1-oxacephems have been achieved through the intramolecular Wittig condensations of 4-(1-methylpropoxy)azetidinones

Novel 2-Methyl-1-oxacephalosporins 1. Synthesis of 2-Methyl-3-nor-1-oxacephem Nucleus

The 2α- and 2β-methyl-1-oxacephems were synthesized stereoselectively starting from (3R,4S)-oxazolinoazetidinone by reaction with chiral alcohols followed by intramolecular carbene insertion of α-diazo-β-keto intermediates

A new synthesis of N-tosylindole from aniline via ortho-substituted N-tosylanilides

A simple and very efficient synthesis of N-tosylindole is described, based on the acid-catalysed cyclization of ortho-alkylated N-tosylanilides, which can be prepared from aniline and dialkyl sulfide by [2,3]sigmatropic rearrangements