Yelda Kapıcıoğlu

Increased Epicardial Adipose Tissue Thickness on Transthoracic Echocardiography in Patients With Behçet Disease

Owing to the fact that the potential frequency of endothelial dysfunction and early atherosclerosis might be higher in Behçet disease, characterized by acute and chronic inflammatory attacks, it may lead to impairment in flow‐mediated dilatation and an increase in epicardial adipose tissue thickness. Therefore, we aimed to evaluate whether epicardial adipose tissue thickness and brachial artery flow‐mediated dilatation as markers of early atherosclerosis and endothelial dysfunction were associated with Behçet disease.

Evaluation of Vertebral Artery Involvement by Doppler Sonography in Patients With Behçet Disease

Neurologic lesions in Behçet disease are most frequently observed in areas supplied by the vertebrobasilar system. We aimed to evaluate possible vertebral artery involvement by Doppler sonography in patients with Behçet disease.

Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey

Cutaneous leishmaniasis (CL) is a vector‐born parasitic disease characterized by various skin lesions that cause disfiguration if healed spontaneously. Although CL has been endemic for many years in the southern regions of Turkey, an increasing incidence in nonendemic regions is being observed due to returning travelers and, more recently, due to Syrian refugees. Thus far, a limited number of national guidelines have been proposed, but no common Turkish consensus has emerged.

Management of complications of vitamin E injections into the face

Dear Editor, Filler applications can be performed by specialists and even by other doctors who are not trained in this field or the personnel who are nonpractitioners (Kamouna et al., 2015). Besides clinically approved filler materials, some unofficial materials with unknown ingredients sold on the Internet might be also used. The adverse effects due to the injections of vitamin E have been frequently encountered in the literature, recently. A 33-year-old woman has attended to our outpatient clinic with the complaint of red, painful, indurated lesions on her face. She had injected vitamin E gel into the zygomatic region of her own face. After 2 months, there were three nodules, which were 2–4 cm in size, erythematous, indurated, and painful at palpation in both zygomatic regions. There were also 2 cm sized erythema and induration on both eyelids (Figure 1). A punch biopsy from the lesion revealed superficial and deep dermal perivascular, interstitial, and periappendiceal lymphohistiocytic infiltrate beneath the minimally hyperkeratotic epidermis. Telangiectatic capillary vessels were present in the superficial and middle portions of the dermis. The patient was evaluated as having a severe inflammatory reaction due to vitamin E injections. She was treated with systemic 0.5 mg/kg/day methylprednisolone, 1.5 mg/day colchicine, and 200 mg/day doxycycline. Additionally, the combination of 8 mg of steroid, 300 mg of clindamycin, and 50 mg of 5-fluorouracil was applied as 0.3 ml intralesional injections at 1 cm intervals. There were no any complications such as atrophy and telangiectasias due to the intralesional injections. The steroid dose was gradually tapered to zero over the ensuing 3 months. After 3-month treatment, there was approximately 80% regression in the size of the lesions (Figure 2). The most common reactions due to foreign material injections are sclerodermoid reactions, subcutaneous infiltration, edema, hyperpigmentation, and deformation. Also, hepatosplenomegaly, acute kidney failure, disseminated lipogranuloma, and sudden death cases possibly caused by dissemination of the materials via hematologic or lymphatic routes are reported (Kamouna et al., 2015; Rollins, Reiber, Guinee, & Lie, 1997). In our case, we think that there has been a hematologic or lymphatic dissemination, too, because she had the similar reaction also on her eyelids, which were uninjected. The most frequent adverse effect due to lipid and vitamin injection is sclerosis lipogranuloma. In sclerosis lipogranuloma, fibrotic and granulomatous changes occur in subcutaneous fat

The Effect of Skin Sebum, pH, and Moisture on Demodex Infestation in Acne Vulgaris and Rosacea Patients

OBJECTIVE Acne vulgaris is an inflammatory disease involving the pilosebaceous unit. Rosacea is a chronic inflammatory skin disease that affects the face in particular. This study aimed to determine if skin sebum, pH, and moisture affect the number of Demodex spp. in acne vulgaris and rosacea patients. METHODS This study focused on 30 patients each with acne vulgaris and rosacea. As a control group, 60 healthy individuals were included. RESULTS In acne vulgaris patients, when compared to those with Demodex mite more than 5 /cm2 in each area, less than 5/cm2 were found to be oily, acidic, dry or very dry. However, there was no significant difference in moisture value. In patients with rosacea, the skin was acidic and dry in patients those with more than 5/cm2 Demodex mites when compared to those with demodex mite less than 5 /cm2 in patients in each of the right cheek and nose areas. There was no difference in skin oil level. CONCLUSION The oily, acidic, dry, and very dry skin of the acne vulgaris patients and the oily, acidic, and very dry skin of the rosacea patients are factors facilitating the development of Demodex ssp.

Tinea incognito: Case series

Türkderm-Deri Hastalıkları ve Frengi Arşivi Dergisi, Galenos Yayınevi tarafından basılmıştır. Turkderm-Archives of the Turkish Dermatology and Venerology, published by Galenos Publishing. Tinea incognito is a dermatophytic infection which has lost its typical clinical appearance because of inappropriate use of topical or systemic corticosteroids. The clinical manifestations of tinea incognito can mimic many dermatoses such as eczema, psoriasis, allergic contact dermatitis, rosacea, seborrheic dermatitis and atopic dermatitis. The diagnosis of tinea incognito is confirmed by direct KOH (potassium hydroxide) examination ( native preparation), making the fungal cultures from the lesion and histopathological examination in some cases. Systemic antifungal therapy is recommended in the treatment of tinea incognito. Herein, 10 cases of tinea incognito which mimicking various dermatoses were diagnosed and treated in our clinic in 2014 is presented. (Turkderm 2015; 49: 222-5)