Yi Sha

A novel sulphur glycoside from the seeds of Descurainia sophia (L.)

A new sulphur glycoside, named descurainoside (1), and the known compound sinapic acid (2) have been isolated from the seeds of Descurainia sophia (L.) Webb ex Prantl. The structure of 1 has been identified as (1R,6S,8R,9S,10S)-9,10-dihydroxy-4-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-8-(hydroxymethyl)-2,7-dioxa-5-thiabicyclo[4.4.0]decan-3-one by means of physico-chemical properties and spectroscopic methods (1D and 2D NMR, HRMS, ESI-MS).

Triterpenoid saponins from leaves and stems of Panax quinquefolium L.

Abstract In the chemical investigation on the saponin composition of leaves and stems of Panax quinquefolium L., two new minor dammarane saponins, quinquenoside L1 (1) and L2 (2) have been isolated. By means of physico-chemical evidences and spectral analysis their structures were established as 3-O-[β-D-glucopyranosyl-(1-2)-β-D-glucopyranosyl]-20-O-β-D-glucopyranosy-dammara-23,25-diene-3β, 12β, 20(S)-triol (1) and 3-O-[β-D-glucopyranosyl-(1-2)-β-D-glucopyranosyl]-20-O-β-D-D-glucopyranosyl-(24Z)-dammar-24-ene-3β, 12β, 20(S), 26-tetraol (2).

A new nor-lignan from the seeds of Descurainia sophia

A new aryldihydronaphthoic acid, descuraic acid (1), was isolated from the seeds of Descurainia sophia (L.) Webb ex Prantl. The structure of 1 was elucidated by means of physico-chemical properties and spectroscopic methods (1D and 2D NMR, MS). 1 was a new nor-lignan.

Quinquenoside L9 from leaves and stems of Panax quinquefolium L.

Abstract During additional chemical investigation on the saponin composition of leaves and stems of Panax quinquefolium L, a new minor dammarane saponin, quinquenoside L9 (1) has been obtained. By means of physico-chemical evidences and spectral analysis, its structure was elucidated as 6-O-[α-L-rhamnopyranosyl-(1–2)-β-D-glucopyranosyl]-dammara-3β,6β,12β,20(S),24ζ,25-hexaol (1).

Triterpenoid prosapogenols and prosapogenins from the husks of Xanthoceras sorbifolia.

Two new prosapogenins, 16-O-acetyl-21-O-(4-angeloyl)-α-l-rhamnopyranosyl barringtogenol C (1), 28-O-β-d-glucopyranosyl 16-deoxybarringtogenol C (2), were isolated from the acid hydrolyzate of the crude saponin obtained from the husks of Xanthoceras sorbifolia Bunge, along with six known triterpenoids. These structures were established on the basis of chemical and detailed spectral evidences. Compounds 1 and 2 showed cytotoxic activity against human cell lines (A375-S2, HeLa).

Norisoprenoids from Ulva lactuca

Five norisoprenoids were isolated from the green marine alga Ulva lactuca. Two new compounds were assigned to (3R,5R,6R,7E)3,5,6-trihydroxy-7-megastigmen-9-one (1) and (3S,5R,6S,7E)3,5,6-trihydroxy-7-megastigmen-9-one (2). The structures and absolute configurations of the five compounds were determined by analyses of NMR, MS and circular dichroism (CD).

A new perylenequinone from the fruit bodies of Bulgaria inquinans

A new perylenequinone, 4,9-dihydroxy-1,2,11,12-tetrahydroperylene-3,10-quinone (1), together with three known compounds, have been isolated from the ethanolic extract of the fruit bodies of Bulgaria inquinans, and their structures elucidated on the basis of the spectral data and comparison with the literature.

Structure elucidation and NMR assignments of an unusual triterpene saponin derivative from Ilex kudincha

One unusual triterpenoid derivative, ilekudinchoside E (1), was isolated from the leaves of Ilex kudincha. The structure was established by various spectroscopic techniques, including one‐ and two‐dimensional NMR, HRTOFMS and CD spectra. Copyright

A new triterpene glycoside from Asterias rollentoni

A new triterpene glycoside, rollentoside A, has been isolated from Asterias rollentoni Bell and identified as 3β-O-{3-O-methyl-β-d-xylopyranosyl-(1 → 3)-O-β-d-glucopyranosyl-(1 → 4)-O-β-d-quinopyranosyl-(1 → 2)-O-β-d-xylopyranosyl}-16-β-acetoxy-23S-acetoxy-holost-7-ene (1), together with a new natural product, rollentoside B (2). The structures of compounds 1 and 2 were elucidated by extensive 1D and 2D NMR investigation (1H–1H COSY, TOCSY, HSQC, HMBC, NOESY).

Two new sesquiterpene lactone glycosides from Artemisia frigida Willd.

The investigation of EtOAc-soluble fraction from the aerial parts of Artemisia frigida has led to the isolation of two new sesquiterpene lactone glycosides, named as artemofriginoside A and artemofriginoside B. Their structures were characterized as 3β-(β-d-glucopyranosyloxy)-8β-(p-hydroxyphenylacetyloxy)-4(15),10(14),11(13)-guaiatrien-1α,5β,6β,7αH-12,6-olide (1) and β-(β-d-glucopyranosyloxy)-8β-(2-hydroxy-3-methylbutanoyloxy)-4(15),10(14),11(13)-guaiatrien-1α,5β,6β,7αH-12,6-olide (2), on the basis of 1D and 2D NMR spectral analysis.