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Yiying Zhang

Howard Hughes Medical Institute

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Publication

Featured researches published by Yiying Zhang.

Nature Medicine | 1995

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Margherita Maffei; Jeffrey L. Halaas; E. Ravussin; R.E. Pratley; G.H. Lee; Yiying Zhang; H. Fei; S. Kim; R. Lallone; S. Ranganathan; P.A. Kern; Jeffrey M. Friedman

Leptin, the gene product of the obese gene, may play an important role in regulating body weight by signalling the size of the adipose tissue mass. Plasma leptin was found to be highly correlated with body mass index (BMI) in rodents and in 87 lean and obese humans. In humans, there was variability in plasma leptin at each BMI suggesting that there are differences in its secretion rate from fat. Weight loss due to food restriction was associated with a decrease in plasma leptin in samples from mice and obese humans.

Nature | 1994

Positional cloning of the mouse obese gene and its human homologue.

Yiying Zhang; Ricardo Proenca; Margherita Maffei; Marisa Barone; Lori Leopold; Jeffrey M. Friedman

Proceedings of the National Academy of Sciences of the United States of America | 1995

Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus

Margherita Maffei; Hong Fei; Gwo-Hwa Lee; C. Dani; P. Leroy; Yiying Zhang; Ricardo Proenca; R. Negrel; G. Ailhaud; Jeffrey M. Friedman

Archive | 1995

Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca

Archive | 1995

Obesity (OB) peptides capable of modulating body weight of animals, allelic variants, analogs and fragments thereof, derivatives, nucleic acid sequences, vect

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca; Margherita Maffei; Jeffrey L. Halaas; Ketan S. Gajiwala; Stephen K. Burley

Archive | 1999

Methods of treating diabetes mellitus with OB polypeptides

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca

Archive | 1997

The weight-regulating agents, and the like nukseiinihapot proteins and their diagnostic and therapeutic uses

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca; Margherita Maffei; Jeffrey L. Halaas; Ketan S. Gajiwala; Stephen K. Burley

Archive | 1995

Modulateurs de masse corporelle, proteines et acides nucleiques correspondants, et utilisations a des fins therapeutiques et diagnostiques

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca; Margherita Maffei; Jeffrey L. Halaas; Ketan S. Gajiwala; Stephen K. Burley

Archive | 1995

Modulatoren von dem körpergewicht, entsprechende nukleinsaüre und proteine, und diagnostische und therapeutische anwendungen davon Modulators of the body weight, corresponding nukleinsaüre and proteins, and diagnostic and therapeutic applications thereof

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca; Margherita Maffei; Jeffrey L. Halaas; Ketan S. Gajiwala; Stephen K. Burley

Archive | 1995

Modulatoren des Körpergewichts, korrespondierende Nukleinsäuren und Proteine, und diagnostische und therapeutische Verwendungen derselben Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof

Jeffrey M. Friedman; Yiying Zhang; Ricardo Proenca; Margherita Maffei; Jeffrey L. Halaas; Ketan S. Gajiwala; Stephen K. Burley

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Jeffrey M. Friedman

Rockefeller University

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Ricardo Proenca

Rockefeller University

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Margherita Maffei

University of Pisa

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Jeffrey L. Halaas

Rockefeller University

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Ketan S. Gajiwala

Pfizer

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Stephen K. Burley

Rockefeller University

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Lori Leopold

Rockefeller University

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