Yong Hyun Cho
Catholic University of Korea
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Featured researches published by Yong Hyun Cho.
Journal of Korean Medical Science | 2010
Chul Sung Kim; Min Eui Kim; Yong Hyun Cho; In Rae Cho; Gilho Lee
To clarify the characteristics of the virulence factors (VFs) of ciprofloxacin resistant Escherichia coli (CFRE) with acute uncomplicated cystitis (AUC), we determined the VFs and the phylogenetic background of all 54 CFRE strains and the 55 randomly selected ciprofloxacin sensitive E. coli strains (CFSE) from patients with AUC in 22 Korean hospitals. The prevalence of the VFs was as follows: fimA, papEF, papGIII, sfaI, dafaBC, cnf1, and hlyA were presented in 96%, 54%, 68%, 91%, 49%, 72%, and 29% of the samples, respectively. The expressions of papEF, cnf1, and hlyA were significantly more prevalent in the CFSE. Moreover, the expressions of cnf, and papEF significantly reduced the risk of ciprofloxacin resistance. The CFSE was also marginally associated with the group B2 (P=0.05). Although the presence of pyuria and a previous cystitis history were not related with the phylotyping and the expressions of VFs, group B2, and fimA and papEF were more expressed in the younger age patients (P<0.05). In conclusion, the CFRE exhibits a selective loss of VFs and the non-B2 phylotype in Korean AUC patients. The group B2 and the presence of fimA and papEF are associated with a younger age of AUC patients.
International Journal of Infectious Diseases | 2016
Dong Sup Lee; Hyun-Sop Choe; Hee Youn Kim; Je Mo Yoo; Woong Jin Bae; Yong Hyun Cho; Sun Wook Kim; Chang Hee Han; Sang Rak Bae; Hoon Jang; Su Bum Park; Byung Il Yoon; Seung-Ju Lee
OBJECTIVES To identify the age- and sex-specific antimicrobial susceptibility patterns of Gram-negative bacteria (GNB) in outpatient febrile urinary tract infections (UTIs) in Korea. METHODS A total 2262 consecutive samples collected from patients aged 1-101 years with febrile UTIs, during the period January 2012 to December 2014, were analyzed in this multicentre, retrospective cohort study. RESULTS The sensitivities to cefotaxime and cefoxitin were over 85% for females but under 75% for males. Sex played an important role in the susceptibility of GNB to cefotaxime (p<0.001) and cefoxitin (p<0.001). The sensitivity to ciprofloxacin (age >20 years) was under 75% in both sexes, and was not influenced by sex (p=0.204). Age distributions of the incidences of resistance to cefotaxime, cefoxitin, and ciprofloxacin (age >20 years) were similar to the age distribution of the incidence of GNB, which indicates that the resistance patterns to these drugs were not affected by age (Kolmogorov-Smirnov test, female/male: p=0.927/p=0.509, p=0.193/p=0.911, and p=0.077/p=0.999, respectively). CONCLUSIONS Age is not a considerable factor in determining the antibiotic resistance in febrile UTIs. Ciprofloxacin should be withheld from both sexes until culture results indicate its use. Second- or third-generation cephalosporins such as cefoxitin and cefotaxime can be used empirically only in females.
Korean Journal of Urology | 2001
Yong Seok Lee; Myung Sik Shin; Yong Hyun Cho
Korean Journal of Urology | 2007
Yong Sun Choi; Yong Hyun Cho; Chang Hee Han
Korean Journal of Urology | 2006
Choung Soo Kim; Sungchan Park; Sang Bok Lee; Jungmin Lee; Han Chung; Moon Kee Chung; Duck Ki Yoon; Jun Cheon; Wun-Jae Kim; Byung Ha Chung; Sung Joon Hong; Jae Mann Song; Sung Goo Chang; Han Yong Choi; Joung Sik Rim; Yong Hyun Cho; Kyung Hyun Moon; Bup Wan Kim
Korean Journal of Urology | 2006
Yong Hyun Cho
Infection and Chemotherapy | 2009
Su Yeon Cho; Ho Jae Lee; Yong Hyun Cho; Seung Ju Lee
Korean Journal of Urology | 2007
Seung Ju Lee; Su Jin Kim; Yong Hyun Cho; Young Nam Woo; Bup Wan Kim; Sung Goo Chang; Min Eui Kim; Chul Sung Kim; Jeong Gu Lee; Bong Suck Sim; Hyung Jin Kim; Byung Ha Chung; In Rae Cho; Sang Don Lee
Infection and Chemotherapy | 2009
Su Yeon Cho; Woong Jin Bae; Yong Hyun Cho; Seung Ju Lee
Korean Journal of Urology | 2006
Jo Un Jung; Dong Wahn Sohn; Yong Hyun Cho