Yong-xiang Ma

Solvent-free synthesis of ferrocenylethene derivatives

Abstract Herein, we report a fast, mild, efficient and simple Wittig reaction in a dry state to get ferrocenylethene derivatives. The Z and E isomers can be separated by chromatography and many isomers are characterized for the first time.

FERROCENYL THIOSEMICARBAZONE AND ITS TRANSITION-METAL COMPLEXES

A new ligand, 1-acetylferrocene-4-phenylthiosemicarbazone (HAfpt), and some transition metal complexes have been prepared. The complexes were characterized by elemental analyses, molar conductivities, IR, NMR, UV and thermal analyses. It is shown that the HAfpt coordinates to the metal ion in a thio-enol form and is a bidentate ligand.

Conversion of tributylstannylferrocene to a variety of heteroaryl ferrocenes

Abstract Tributylstannylferrocene (FcSnBu 3 ) was converted to a variety of heteroaryl ferrocenes, such as 2-thiophenyl, 3-thiophenyl, 3-pyridyl, 3-quinolyl, 4-oxazolyl and 4-isoxazolyl ferrocene, by using Pd-catalyzed reactions. The Stille-coupling catalyst (PdCl 2 –PPh 3 ) promotes the reaction between FcSnBu 3 and electron-deficient heterocyclic bromides, while a modified catalyst (Pd–Ph 3 P–CuO) proves to be the choice for the coupling of FcSnBu 3 with electron-rich heterocyclic bromides.

Bromination of ferrocene chalcone derivatives mediated by β-cyclodextrin

Abstract Bromination of the inclusion complex of trans -ferrocenylchalcone derivatives with β-cyclodextrin was studied. In the absence of β-cyclodextrin, the analogous ferrocenylchalcone does not undergo bromination at room temperature, but its inclusion complex in β-cyclodextrin brominates smoothly and gives the erythro -dibromide derivatives. This complexation does not induce any variation in the bromination pattern and the ferrocenyl moiety is not attacked in the reaction. These observations have been accounted for in terms of guest–host interaction patterns. The formation of complex and dibromination product has been confirmed by elemental analyses, IR, 1 H-NMR, 13 C-NMR, UV–Vis and electrochemical methods.

An Improving Method For the Preparation of Ethynylferrocene

Abstract Ethynylferrocene was prepared in satisfactory yield by reaction of formylferrocene with triphenylphosphine and carbon tetrachloride followed by dehydrohalogenation in presence of n-butyllithum. The reaction condition is mild and the reaction time is much shorter. The method is convenient and economical.

Preparation of 1,5-diketone derivatives containing ferrocenyl by Michael reaction under solvent-free condition

Abstract This work describes a fast, mild, convenient and simple method for preparing 1,5-diketones by Michael reaction under solvent-free condition. Fourteen new 1,5-diketone compounds containing ferrocenyl were synthesized. The product 1f is discussed from its 1 H-NMR spectrum.

Synthesis of novel chalcone analogues of ferrocene biarenes

Abstract The novel structures of organometallic compounds, 1-biaryl-3-ferrocenyl-2-propene-1-one (5) and 3-biaryl-1-ferrocenyl-2-propene-1-one (9) were synthesized for nonlinear optical chromophores by Suzuki cross-coupling reaction. Their structures were determined with elemental analyses, IR spectra, 1H NMR spectra, and 13C NMR spectra.

SOLID-PHASE SYNTHESIS OF FERROCENYLCHALKONE

ABSTRACT A convenient and rapid aldol condensation between acylferrocene and ketone or aldehyde is performed in excellent yield in presence of solid NaOH under mild and solvent-free ‘dry’ conditions.

A Convenient Synthesis of Monosubstituted Ferrocene Heterocycles

Abstract An alternative synthesis of monosubstituted ferrocenylheterocyclic compounds, using impure bis(tributylstannyl)ferrocene and heterocyclic bromides as substrates through Pd-catalyzed selective Stille coupling reaction and subsequent destannylation, is described.

A novel synthesis of 1,1′-unsymmetrical disubstituted heteroarylferrocene

Abstract Stepwise Stille coupling reaction of 1,1′-bis(tributylstannyl)ferrocene with different heterocyclic bromides was achieved in the presence of Pd-complex catalyst via two steps to afford unsymmetrical 1,1′-disubstituted heteroarylferrocene compounds.