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Yongchun Pan

Incyte

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Publication

Featured researches published by Yongchun Pan.

Organic Letters | 2009

Enantioselective Synthesis of Janus Kinase Inhibitor INCB018424 via an Organocatalytic Aza-Michael Reaction

Qiyan Lin; David Meloni; Yongchun Pan; Michael Xia; James D. Rodgers; Stacey Shepard; Mei Li; Laurine Galya; Brian Walter Metcalf; Tai-Yuen Yue; Pingli Liu; Jiacheng Zhou

An enantioselective synthesis of INCB018424 via organocatalytic asymmetric aza-Michael addition of pyrazoles (16 or 20) to (E)-3-cyclopentylacrylaldehyde (23) using diarylprolinol silyl ether as the catalyst was developed. Michael adducts (R)-24 and (R)-27 were isolated in good yield and high ee and were readily converted to INCB018424.

Archive | 2010

Processes for preparing JAK inhibitors and related intermediate compounds

Jiacheng Zhou; Pingli Liu; Qiyan Lin; Brian Metcalf; David Meloni; Yongchun Pan; Michael Xia; Mei Li; Tai-Yuen Yue; James D. Rodgers; Haisheng Wang

Archive | 2009

Salts of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same

Lingkai Weng; Lei Qiao; Jiacheng Zhou; Pingli Liu; Yongchun Pan

Archive | 2014

Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor

Ming Tao; William Frietze; David Meloni; Lingkai Weng; Jiacheng Zhou; Yongchun Pan

Archive | 2017

SALTS OF AN LSD1 INHIBITOR

Yongchun Pan; Wayne Han; Genfeng Cao; William Frietze; Zhongjiang Jia; Vaqar Sharief; Jiacheng Zhou; Qun Li

Archive | 2017

SALTS OF A PIM KINASE INHIBITOR

Zhongjiang Jia; Ganfeng Cao; Qiyan Lin; Yongchun Pan; Lei Qiao; Vaqar Sharief; Chongsheng Eric Shi; Michael Xia; Changsheng Zheng; Jiacheng Zhou; Qun Li

Archive | 2016

SALTS AND PROCESSES OF PREPARING A PI3K INHIBITOR

Lei Qiao; Lingkai Weng; Chongshen Eric Shi; David Meloni; Qiyan Lin; Michael Xia; Vaqar Sharief; William Frietze; Zhongjiang Jia; Yongchun Pan; Pingli Liu; Tai-Yuen Yue; Jiacheng Zhou

Archive | 2017

SALES DE UN INHIBIDOR DE LSD1

Qun Li; Jiacheng Zhou; Vaqar Sharief; Zhongjiang Jia; William Frietze; Ganfeng Cao; Wayne Han; Yongchun Pan

Archive | 2017

SALES Y PROCESOS DE PREPARACIÓN DE UN INHIBIDOR DE PI3K

Jiacheng Zhou; Tai Yue; Pingli Yuen Liu; Yongchun Pan; William Frietze; Zhongjiang Jia; Vaqar Sharief; Michael Xia; Qiyan Lin; David Meloni; Chongshen Eric Shi; Lingkai Weng; Lei Quiao

Archive | 2017

sais de 2-flúor-n-metil-4-[7-(quinolin-6-il-metil)-imidazo[1,2-b][1,2,4]triazin-2-il]benzamida e processos relacionados à preparação dos mesmos

Jiacheng Zhou; Lei Qiao; Lingkai Weng; Pingli Liu; Yongchun Pan

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Jiacheng Zhou

Incyte

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Michael Xia

Incyte

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Qiyan Lin

Incyte

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David Meloni

Incyte

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Lei Qiao

Incyte

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Lingkai Weng

Incyte

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Pingli Liu

Incyte

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Vaqar Sharief

Incyte

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Zhongjiang Jia

Incyte

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Tai-Yuen Yue

Incyte

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