Yoo-Kyung Sohn

Intraamniotic infection with genital mycoplasmas exhibits a more intense inflammatory response than intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes

OBJECTIVE The objective of the study was to compare the intensity of inflammatory responses between intraamniotic infection with genital mycoplasmas and intraamniotic infection with other microorganisms. STUDY DESIGN We examined the intensity of intraamniotic and maternal inflammatory responses in 99 patients with preterm premature rupture of membranes and a positive amniotic fluid (AF) culture. AF was obtained by transabdominal amniocentesis or at the time of cesarean delivery. Patients were divided according to the recovered microorganisms: (1) genital mycoplasmas (n = 62); (2) other microorganisms (n = 31); or (3) mixed infection (n = 6). RESULTS The median AF white blood cell (WBC) count, maternal blood WBC count, and plasma C-reactive protein concentrations were significantly higher in patients with intraamniotic infection with genital mycoplasmas than in those with intraamniotic infection with other microorganisms (P < .05 for each). CONCLUSION Intraamniotic and maternal inflammatory responses are more intense in intraamniotic infection with genital mycoplasmas than in intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes.

Fetal hydronephrosis – natural history and predictors of postnatal outcome

Objectives:  The aim of this study was to evaluate the natural history of antenatally detected hydronephrosis and to assess the relationship between the severity of fetal hydronephrosis and postnatal outcome.

P12.09: Histologic chorioamnionitis after multifetal pregnancy reduction: is it a risk factor for preterm delivery?

of amnioinfusion was 658 ± 220 cc. The mean pre-op MVP was significantly different between the SP and NSP groups (8.7 ± 0.6 vs. 11.0 ± 0.2 cm, p < 0.05). The mean gestational age (GA) was not different (20.3 ± 1.9 vs. 19.7 ± 6.5 weeks). There was no correlation between MVP and GA (r = .03, p = .72). There was no difference in Stage (p = .08), with 11/16 (68%) SP patients being Stage III or IV. Conclusion: An SP is present in 12% of patients with TTTS, despite polyhydramnios. Amnioinfusion is required for SLPCV in patients with SP to disclose all anastomotic vessels. As a corollary, therapeutic amniocenteses prior to laser surgery may result in iatrogenic development of SP, requiring intraoperative amnioinfusion.