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Publication
Featured researches published by Yoshifumi Hayashi.
international conference on biomedical engineering | 2014
Yasutaka Tobe; Takanobu Yagi; Yuki Iwabuchi; Momoko Yamanashi; Kenji Takamura; Takuma Sugiura; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Atsushi Nakajima; Kazutoshi Nishitani; Yoshifumi Okada; Michihito Sugawara; Shin Hiraguchi; Toshiro Kubo; Shigemi Kitahara
This research compared the intraoperative appearance, computational fluid dynamic (CFD) analysis, and scanning electron microscope (SEM) observation of endothelial cells (EC) of seven human cerebral aneurysms in an effort to find the relationship between hemodynamic patterns and wall-thinning of aneurysms.
Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments | 2013
Yasutaka Tobe; Takanobu Yagi; Yuki Iwabuchi; Momoko Yamanashi; Kenji Takamura; Kiyotaka Iwasaki; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Atsushi Nakajima; Kazutoshi Nishitani; Yoshifumi Okada; Michihito Sugawara; Shin Hiraguchi; Toshiro Kubo; Shigemi Kitahara
Cerebral aneurysms are known as the top reason of subarachnoid hemorrhage (SAH). They are studied in the medical and the engineering field to reveal their pathogenesis, progression, and rupture mechanisms1,2. The pathological studies revealed the site of predilection, rupture rate, the risk factors1, inflammation within the aneurysm, and conditions of endothelial cells (EC) in the aneurysms3. The current pathological analyses of the cerebral aneurysms are all phenomenological and it does not consider the cause-and-effect mechanisms between the mechanical stimulation and the physiological effect although hemodynamics is thought to play an important role in the mechanisms of aneurysms. One reason that the aneurysms’ mechanisms remain unsolved is because the pathology and hemodynamics are studied independently. Purpose of this study is to reveal the relationship of endothelial cell, thickness, and hemodynamics of the cerebral aneurysms by comparing the scanning electron microscope (SEM) analyses, μCT, and the computational fluid dynamics (CFD) analyses of the cerebral aneurysms.© 2013 ASME
ASME 2012 Summer Bioengineering Conference, Parts A and B | 2012
Yasutaka Tobe; Takanobu Yagi; Sara Takahashi; Yuki Iwabuchi; Momoko Yamanashi; Kiyotaka Iwasaki; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Yoshifumi Okada; Michihito Sugawara; Shin Hiraguchi; Toshiro Kubo; Shigemi Kitahara
Recent studies of cerebral aneurysms are held using the blood flow simulation with patient-specific luminal geometries. In the study of development of cerebral aneurysms, wall shear stress (WSS) is focused as one of the key factors1–2. But the answer to the relationship between the extension of aneurysm and the theory of low WSS and high WSS still remains a question. One reason this question remains unsolved is because the current research about the cerebral aneurysms are held only using the vascular geometry developed from the medical images. From the intra-operative observation of cerebral aneurysms, the appearance of the cerebral aneurysm is not unified. Certain parts of the cerebral aneurysm have thin-walled structures where the blood flow of the aneurysm can be observed through the aneurysm wall. These differences in the wall structures cannot be predicted from the medical images. The purpose of this study is to see the relationship between hemodynamic patterns and thin-walled structure in human cerebral aneurysms.Copyright
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2017
Yasutaka Tobe; Takanobu Yagi; Kenta Suto; Shinnei Ou; Koichi Kawamura; Mitsuo Umezu; Hirotaka Yoshida; Yoshifumi Hayashi; Kazutoshi Nishitani; Yoshifumi Okada
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2016
Yasutaka Tobe; Takuma Sugiura; Kenta Suto; Takanobu Yagi; Koichi Kawamura; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Yoshifumi Okada; Shigemi Kitahara
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2016
Takuma Murayoshi; Takanobu Yagi; Yasutaka Tobe; Takuma Sugiura; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Toshifumi Okada; Shigemi Kitahara
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2016
Kiyofumi Takanishi; Takanobu Yagi; Mikihiko Watanabe; Mitsuo Umezu; Masanori Nakamura; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Yoshifumi Okada; Shigemi Kitahara
The Proceedings of the JSME Conference on Frontiers in Bioengineering | 2015
Yasutaka Tobe; Takuma Sugiura; Koichi Kawamura; Takanobu Yagi; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Yoshifumi Okada; Shigemi Kitahara
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2015
Takuma Murayoshi; Yasutaka Tobe; Takuma Sugiura; Takanobu Yagi; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Yoshifumi Okada; Shigemi Kitahara
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2015
Takuma Sugiura; Takanobu Yagi; Koichi Kawamura; Yasutaka Tobe; Mitsuo Umezu; Yoshifumi Hayashi; Hirotaka Yoshida; Kazutoshi Nishitani; Yoshifumi Okada; Shigemi Kitahara
