Yu-Ming Chi

Four monoterpene alkaloid derivatives from Incarvillea sinensis

Two new derivatives of monoterpene alkaloids, named incarvillateine C and incarvillateine D which are related to an antinociceptive alkaloid, incarvillateine, were isolated from the aerial parts of Incarvillea sinensis LAM. On the basis of both chemical and spectroscopic evidence, the structures of the first two were characterized as a bis-demethoxy and demethoxy derivatives of incarvillateine, respectively.

Two alkaloids from Incarvillea sinensis

Two novel ester alkaloids, incarvines B and C, were isolated from the aerial parts of Incarvillea sinensis. On the basis of chemical and spectroscopic evidence, incarvine B was characterized as the ester of the monoterpene alkaloid, incarvilline, and the monoterpene acid, Hildebrandts acid, whilst the structure of incarvine C was established as incarvilline 7-O-ferulate.

Incarvine A, a monoterpene alkaloid from Incarvillea sinensis

A novel ester compound comprised of a monoterpene alkaloid and a monoterpene, named incarvine A, has been isolated from Incarvillea sinensis. Its chemical structure was characterized by chemical and spectroscopic means.

A novel macrocyclic spermine alkaloid from Incarvillea sinensis.

A novel macrocyclic spermine alkaloid incasine C′ (1), along with a known compound incasine C (2), were isolated from the whole plants of Incarvillea sinensis, and their structures were elucidated on the basis of chemical and spectroscopic evidence.