Yukio Tsugu

小腸運動におけるinterdigestive migrating electric complexの興奮伝播様式と調節機構について

Segments and Thirty-Vella type loops of the small intestine of dogs were prepared, and the excitation propagation pattern of the interdigestive migrating electric complex (IMEC) was observed by electromyography. The nerve regulatory mechanism in intestinal movement was investigated. The results indicated that first, the frequency of the basic electric rhythm (BER) is controlled so that a downward gradient is formed from the upper to the lower intestine, but this gradient continues to be controlled by a two-dimensional control mechanism involving parietal factors and extrinsic nerves due to transection of the intestines and damage to the extrinsic nerves in the dominant region. However, propagation of the IMEC in the small intestine appeared to be regulated by a combination of the two-dimensional control mechanism involving extrinsic and parietal nerves corresponding to the BER control mechanism. It was clear that the propagation mechanism of IMEC is related to the BER frequency, and propagation of the IMEC is downward in accordance with the frequency gradient of BER.

Studies on postoperative disorders in small bowel

In the group of 70% partial hepatectomy, 4 rats out of 15, were survived at operation. 2 ra ts were found to have hepatom or adenom, respectively. In the electron microscopic study, the nucleus membrane of tumor cell were irregular and vacuole were scattered in cytoplasma. Mitochondria were deformed and endoplasmic reticulum were revealed canalicular formation in all groups. Hence, it is concluded that prolongation of survival was noted in the ligated ra ts as compared to that in control rats. This prolongation may depend on the interruption of portal flow to the hepatom and liver regenerat ion on the non-ligated lobes.

Studies on postoperative disorders of the bowel

However, the fatty acid composition of the plasma lipids was generally constant during the fat absorption. On the other hand, the fattyacid composition of the thoracic duct lymph showed a considerable resemblance to taht of linseed oil. However, in some dogs, the total fatty acid levels of the lymph increased markedly as soon as the fat was administered enterally, and they were little accompanied with the increase either of the radioactivity or of linolenic acid. These findings in the present study indicate distinctly that; (1) Long chain fatty acids can be absorbed directly into the portal blood. (2) The lymph collected through the thoracic duct cannula contains a considerable amount of endogenous fatty acids even in the period of the intestinal fat absorption.