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Dive into the research topics where Yumiko Kaku is active.

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Featured researches published by Yumiko Kaku.


Bioorganic & Medicinal Chemistry Letters | 2002

A library construction of 2,5-disubstituted pyrrole compounds by using solid/solution-phase syntheses.

Naoki Kobayashi; Yumiko Kaku; Kunizo Higurashi; Toshihiko Yamauchi; Akira Ishibashi; Yasushi Okamoto

Using solid- and solution-phase synthesis, a library of 2,5-disubstituted pyrrole compounds was constructed. This is the first report that Stetter reaction was applied to the solid-phase synthesis for C-C bond formation. Some of 2,5-disubstituted pyrrole compounds showed the inhibitory activity of LPS-induced mouse B-lymphocyte proliferation.


Chemical & Pharmaceutical Bulletin | 1998

Synthesis and antifungal activity of novel thiazole-containing triazole antifungals. II. Optically active ER-30346 and its derivatives.

Akihiko Tsuruoka; Yumiko Kaku; Hiroyuki Kakinuma; Itaru Tsukada; Manabu Yanagisawa; Kazumasa Nara; Toshihiko Naito


Archive | 1995

Antifungal agents, and compositions

Toshihiko Naito; Katsura Hata; Yumiko Kaku; Akihiko Tsuruoka; Itaru Tsukada; Manabu Yanagisawa; Toshio Toyosawa; Kazumasa Nara


Chemical & Pharmaceutical Bulletin | 1997

Synthesis and Antifungal Activity of Novel Thiazole-Containing Triazole Antifungals

Akihiko Tsuruoka; Yumiko Kaku; Hiroyuki Kakinuma; Itaru Tsukada; Manabu Yanagisawa; Toshihiko Naito


Chemical & Pharmaceutical Bulletin | 1998

A Novel Route for Chiral Synthesis of the Triazole Antifungal ER-30346

Yumiko Kaku; Akihiko Tsuruoka; Hiroyuki Kakinuma; Itaru Tsukada; Manabu Yanagisawa; Toshihiko Naito


Archive | 1995

Azole antifungal agents, process for the preparation there of and intermediates

Toshihiko Naito; Katsura Hata; Yumiko Kaku; Akihiko Tsuruoka; Itaru Tsukada; Manabu Yanagisawa; Toshio Toyosawa; Kazumasa Nara


Archive | 1995

Azole antifungal agents, processes for the preparation thereof, and intermediates

Toshihiko Naito; Katsura Hata; Yumiko Kaku; Akihiko Tsuruoka; Itaru Tsukada; Manabu Yanagisawa; Toshio Toyosawa; Kazumasa Nara


Archive | 2002

Conbinatorial library of heterocycle compounds

Naoki Kobayashi; Yasushi Okamoto; Kunizo Higurashi; Yumiko Kaku; Akira Ishibashi; Toshihiko Yamauchi


Archive | 2001

Antifungal agent and its preparation method and intermediate

Toshihiko Naito; Katsura Hatake; Yumiko Kaku


Archive | 1997

INTERMEDIATE 1-(PHENYLALKYL)-TRIAZOLE AND -IMIDAZOLE DERIVATIVES AND PREPARATION THEREOF

Toshihiko Naito; Katsura Hata; Yumiko Kaku; Akihiko Tsuruoka; Itaru Tsukada; Manabu Yanagisawa; Toshio Toyosawa; Kazumasa Nara

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