Yvonne Fischer
University of Ulm
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Featured researches published by Yvonne Fischer.
Laryngoscope | 2010
Yvonne Fischer; Martin Khan; Wolf J. Mann
Objectives/Hypothesis: The concept of two‐level pharyngeal collapse in patients with obstructive sleep apnea is too simplified. Aggressive multilevel surgeries addressing several airway segments, including skeletal surgery, demonstrate improved success rates. Study Design: The study aimed to evaluate the safety and efficacy of multilevel radiofrequency application to soft palate, tonsils, and base of tongue in 16 white patients (mean age, 56.9 ± 11.1 y; mean body mass index, 27.3 ± 2.6 kg/m 2 ) with obstructive sleep apnea. There was one dropout. Therapeutic effects after one treatment session were assessed 20.6 ± 12.6 weeks postoperatively. Treatment outcome measurements were based on Epworth Sleepiness Scale, Likert scales, and polysomnography. Methods: Every patient received 16 treatment sites with a total dose of 9750 J radiofrequency energy into soft palate, base of tongue, and tonsils. Success was defined as respiratory disturbance index equal to or less than 20 or at least 50% improvement if baseline respiratory disturbance index was less than 20. Statistical analysis was determined with the Spearman rank test. Results: Mean score on Epworth Sleepiness Scale decreased from 11.1 to 8.2 (P = .0001). Of the patients, 53.3% reported improvement of their daytime sleepiness. Snoring was assessed with 10‐point Lickert scale, and score decreased from 7.5 to 4.9 (P = .08). Mean respiratory disturbance index decreased from 32.6 δ 17.4 to 22.0 δ 15.0 (P = .003). By our definition of success, 5 of 15 patients (33%) have been treated successfully surgically and 4 of 15 (27%) had remarkable improvement after one treatment session; 1 patient (6.6%) demonstrated deterioration. There were two adverse effects, one superficial ulceration of the soft palate and one unilateral tonsillar abscess formation, with an overall complication rate of 13.3% for our patients and 0.41% for all treatment sites (n = 240). Conclusion: Moderate to severe obstructive sleep apnea usually requires multilevel pharyngeal surgery. Radiofrequency offers the potential of altering the upper airway on different sites.
American Journal of Rhinology | 2000
Yvonne Fischer; Jan Gosepath; Ronald G. Amedee; Wolf J. Mann
Twenty-two Caucasians (16 male and 6 female) with chronic bilateral nasal obstruction due to hypertrophic inferior turbinates were followed up over a three-month period. They were assessed by clinical examination, as active anterior rhinometry, and acoustic rhinometry before and after topical decongestion, preoperatively and three months after surgery. All patients were treated by application of radiofrequency-volumetric-tissue reduction (RFVTR, or somnoplasty) to both inferior turbinates. Initial postoperative edematous response disappeared during the first week after RFVTR. Three months postoperatively 20 of 22 patients (91%) reported subjective improvement of nasal patency. The average cross-sectional area for both sides of the nasal cavity (measured at the head of the inferior turbinate (C-Notch) before decongestion) increased in 15 of 22 patients (68.2%). This means a significant improvement from 1.24 to 1.49 cm2 for both sides of the nasal cavity (p = 0.0054). We conclude that RFVTR can safely reduce turbinate volume in a precise manner in patients with nasal obstruction due to hypertrophic inferior turbinates.
Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2006
Ajnacska Rozsasi; Richard Leiacker; Yvonne Fischer; Tilman Keck
The aim of this study was to evaluate changes in total respiratory heat loss during use of a heat and moisture exchanger (HME) in tracheotomized patients.
American Journal of Rhinology | 2006
Yvonne Fischer; Silke Gronau; Ajnacska Rozsasi; Gerhard Rettinger; Philipp M. Gruen
Background The aim of this study was to determine the effects of radiofrequency-induced thermotherapy (RFITT) in patients with nasal polyps. Methods A retrospective analysis was performed of prospectively collected data from 17 consecutive patients (11 men and 6 women; mean age, 51.7 ± 16.9 years) treated with RFITT from 2002 to 2003. The postoperative outcome was assessed using active anterior rhinomanometry, “sniffin’ stick” test, and endoscopic nasal examination preoperatively and 4 weeks postoperatively. Subjective complaints were assessed with Likert scales. Results Transnasal airflow increased by 40.3% 4 weeks postoperatively (p = 0.029). Endoscopic appearance of nasal polyps indicated a nonsignificant reduction of 37.1%. Subjective complaints such as impaired nasal ventilation (p = 0.014), nasal discharge (p = 0.0007), postnasal drip (p = 0.0002), and hyposmia (p = 0.048) improved significantly 4 weeks after surgery. Conclusion RFITT is well tolerated as a day case procedure under local anesthesia and might be a procedure for treating recurrence of NP after sinus surgery. It remains unclear at this point whether RFITT for nasal polyps results in a permanent reduction.
Sleep and Breathing | 2008
Yvonne Fischer; Tilman Keck; Richard Leiacker; Ajnacska Rozsasi; Gerhard Rettinger; Philipp M. Gruen
Laryngo-rhino-otologie | 2006
Yvonne Fischer; Neagos A; Silke Gronau; Gerhard Rettinger
Hno | 2003
Yvonne Fischer; A. Yakinthou; Wolf J. Mann
Hno | 2003
Yvonne Fischer; A. Yakinthou; Wolf J. Mann
Laryngo-rhino-otologie | 2005
Yvonne Fischer; Silke Gronau
Hno | 2003
Yvonne Fischer; A. Yakinthou; Wolf J. Mann