Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Zahi Fayad is active.

Publication


Featured researches published by Zahi Fayad.


Clinical Medicine Insights: Cardiology | 2014

Inflammation, Atherosclerosis, and Coronary Artery Disease: PET/CT for the Evaluation of Atherosclerosis and Inflammation

Nadia Alie; Mootaz Eldib; Zahi Fayad; Venkatesh Mani

Atherosclerosis is a prevalent cardiovascular disease marked by inflammation and the formation of plaque within arterial walls. As the disease progresses, there is an increased risk of major cardiovascular events. Owing to the nature of atherosclerosis, it is imperative to develop methods to further understand the physiological implications and progression of the disease. The combination of positron emission tomography (PET)/computed tomography (CT) has proven to be promising for the evaluation of atherosclerotic plaques and inflammation within the vessel walls. The utilization of the radiopharmaceutical tracer, 18F-fluorodeoxyglucose (18F-FDG), with PET/CT is invaluable in understanding the pathophysiological state involved in atherosclerosis. In this review, we will discuss the use of 18F-FDG-PET/CT imaging for the evaluation of atherosclerosis and inflammation both in preclinical and clinical studies. The potential of more specific novel tracers will be discussed. Finally, we will touch on the potential benefits of using the newly introduced combined PET/magnetic resonance imaging (MRI) for non-invasive imaging of atherosclerosis.


Journal of the American College of Cardiology | 2013

GM-CSF ENHANCES GLYCOLYTIC ACTIVITY IN MACROPHAGES IN VITROAND IMPROVES DETECTION OF ATHEROSCLEROTIC INFLAMMATION IN VIVO

Parmanand Singh; Ahmed Tawakol; Marina Mojena; María Pimentel-Santillana; Zahi Fayad; James Rudd; Paqui G. Través; María del Carmen Díaz Fernández; Alberto Tejedor; Lisardo Boscá

18F-fluorodeoxyglucose (FDG) accumulates in activated macrophages (Mo). Here, we test the hypotheses that GM-CSF, a clinically administered cytokine, augments Mo glycolysis in vitro and enhances imaging of arterial inflammation in vivo. In vitro experiments were conducted in human and murine M


Journal of the American College of Cardiology | 2013

HIGH DOSE ATORVASTATIN REDUCES PERIODONTAL ACTIVITY IN PROPORTION TO ATHEROSCLEROTIC INFLAMMATION: A POTENTIALLY NOVEL PLEIOTROPIC EFFECT OF STATINS

Hamed Emami; Sharath Subramanian; Esad Vucic; Jayanthi Vijayakumar; Kenneth Fifer; Thomas J. Brady; James Rudd; Zahi Fayad; Thomas E. Van Dyke; Ahmed Tawakol

Periodontal disease (PD) is a common, chronic oral inflammatory condition and a risk factor for atherosclerosis (Athero). Here, we assessed whether high-dose atorvastatin (ATV) reduces periodontal (perio) inflammation (using 18F-fluorodeoxyglucose-positron emission tomography/computed tomography [


Jacc-cardiovascular Imaging | 2015

FDG-PET Imaging for Oxidized LDL in Stable Atherosclerotic Disease: A Phase II Study of Safety, Tolerability, and Anti-Inflammatory Activity

Joshua Lehrer-Graiwer; Parmanand Singh; Amr Abdelbaky; Esad Vucic; Magnus Korsgren; Amos Baruch; Jill Fredrickson; Nick van Bruggen; Meina T. Tang; Björn Frendéus; James Rudd; Frank Hsieh; Christie M. Ballantyne; Brian B. Ghoshhajra; Robert S. Rosenson; Michael Koren; Eli M. Roth; Daniel A. Duprez; Zahi Fayad; Ahmed Tawakol


Society of Nuclear Medicine Annual Meeting Abstracts | 2014

PET/MRI to predict and quantify the uptake of 89Zr-labeled nanoparticles in the aortic wall of atherosclerotic rabbits

Tina Binderup; Mark E. Lobatto; Carlos Perez-Medina; Luuk Giesen; Philip M. Robson; Claudia Calcagno; Jason S. Lewis; Thomas Reiner; Zahi Fayad; Willem J. M. Mulder


Archive | 2008

A carrier particle for use in bio-applications

Roelof Koole; Willem Jan Menno Mulder; Schooneveld Matti Miriga Van; Andries Meijerink; Zahi Fayad; Jan Hilhorst


Archive | 2017

Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis

Willem J. M. Mulder; Jordi Ochando; Zahi Fayad; Mounia S. Braza; Raphaël Duivenvoorden; Francois Fay


BSC Doctoral Symposium (2nd: 2015: Barcelona) | 2015

From imaging to simulation: a framework applied to simulate the blood flow in the carotids

Ruth Arís; Venkatesh Mani; Hadrien Dyvorne; M. Jowkar; Alfonso Santiago; Guillaume Houzeaux; Zahi Fayad; Mariano Vázquez


Society of Nuclear Medicine Annual Meeting Abstracts | 2014

Comparison of PET/MRI and PET/CT studies in liver selective internal radiation therapy with 90Y microspheres

Karin Knesaurek; Mootaz Eldib; Zhuangyu Zhang; Jason Bini; Kamil Banibaker; Eric Rodriguez; E. Kim; Sherif Heiba; Zahi Fayad; Lale Kostakoglu


Journal of the American College of Cardiology | 2014

HYPOXIA-INDUCIBLE FACTOR 1-ALPHA REGULATES ATHEROSCLEROSIS VIA MACROPHAGE ACTIVATION AND METABOLIC PATHWAYS

Parmanand Singh; Ahmed Tawakol; Esad Vucic; Hamed Emami; Zahi Fayad; Jagat Narula; James Rudd; Alex Morss; Jeffrey Swanson; Sara Fontanez; Paqui G. Través; Alberto Tejedor; María Pimentel-Santillana; Marina Mojena; Mar_a Fern_ndez-Velasco; Lisardo Boscá

Collaboration


Dive into the Zahi Fayad's collaboration.

Top Co-Authors

Avatar

James Rudd

Spanish National Research Council

View shared research outputs
Top Co-Authors

Avatar

Josef Machac

Icahn School of Medicine at Mount Sinai

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Venkatesh Mani

Icahn School of Medicine at Mount Sinai

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Kelly S. Myers

Icahn School of Medicine at Mount Sinai

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge