Zhi-Min Zong

Hollow zeolite structures formed by crystallization in crosslinked polyacrylamide hydrogels

Hollow zeolite structures including sodalite spheres and hollow zeolite NaA crystals were synthesized by introducing crosslinked polyacrylamide (C-PAM) hydrogels into zeolite synthesis gels. The synthesis gels with weight compositions of 0.8SiO2 : 1.0Al2O3 : 21.2Na2O : 86.0H2O : 7.4–28.7 acrylamide (AM) were used to produce hollow sodalite spheres. The synthesized hollow sodalite spheres had diameters of 1–5 μm and shell thicknesses of 0.5–1 μm, and the sphere diameters decreased from 5–10 μm to 1–3 μm as the amount of C-PAM increased. Hollow zeolite A crystals with sizes of 300–500 nm were grown from the synthesis gel with a weight ratio of 0.8SiO2 : 1.0Al2O3 : 2.6Na2O : 16.4H2O : 2.6–3.8AM. The experimental results suggest that the formation of hollow zeolite structures may involve a surface-to-core crystallization process induced by crosslinked polyacrylamide networks.

A Clean Synthesis of 1‐Oxo‐hexahydroxanthene Derivatives in Aqueous Media Catalyzed by TEBA

Abstract A series of 1‐oxo‐1,2,3,4,9,10‐hexahydroxanthene derivatives were synthesized from substituted salicylaldehydes and substituted 1,3‐hexanedione in water at 90°C catalyzed by TEBA. The structure of the product was confirmed by X‐ray analysis. Compared with other synthetic methods, this new method has the advantages of easier workup, milder reaction conditions, high yields (85 ∼ 95%) and environmentally benign procedure.

Advances in the study of hydrogen transfer to model compounds for coal liquefaction

The advances in the study of hydrogen transfer to model compounds for coal liquefaction are reviewed. The results from many model reactions indicate that molecular hydrogen promotes thermolysis, hydrogenation, and hydrocracking of model compounds, whereas hydrogen-donating solvents inhibit the reactions. Unlike metallic catalysts such as Fe, Pd, and Ni, their sulfides catalyze radical hydrogen transfer to model compounds. The reactivities of model compounds toward hydrocracking depend not only on their hydrogen-accepting abilities, but also on their adsorption strength on catalyst surface and the stabilities of the resulting leaving groups.

KF-alumina catalyzed one-pot synthesis of pyrido[2,3-d]pyrimidine derivatives

Abstract A series of pyrido[2,3‐d]pyrimidine derivatives was synthesized by the reaction of arylaldehyde, malononitrile, and 4‐amino‐2,6‐dihydroxylpyrimidine in ethyl alcohol at 80°C catalyzed by KF‐Al2O3. Compared with other synthetic methods, this new method has the advantage of easier workup, milder reaction conditions, and good yields.

Synergic effect of methanol and water on pine liquefaction

Pine liquefaction (PL) and re-liquefaction of its liquefaction residues in sub- and supercritical methanol, water or methanol/water mixed solvents (MWMSs) was investigated. The results show that isometric MWMS has the highest synergic effect on PL. Moreover, the total yield of bio-oil (BO) and conversion from pine and its residue both liquefied in the MWMS were obvious higher than those from PL in methanol (water) and re-liquefaction of its residue in water (methanol), suggesting that the interaction between the two solvents is responsible for synergic effect. This approach facilitates understanding the mechanism for biomass liquefaction in mixed solvents and developing efficient utilization process of biomass.

Separation and analysis of the degradation products of two coals in aqueous NaOCl solution

Abstract Two varieties of coal were oxidized with aqueous NaOCl solution under mild conditions. The reaction mixture acidified was sequentially extracted with ethoxyethane, CS2, petroleum ether, acetic ester and benzene, followed by esterification with CH2N2 and analysis with GC/MS. The results show that the main products are chloro-substituted compounds, aliphatic acids and aromatic polycarboxylic acids. The oxidative product was sequentially extracted with different polar solvents and achieved a simple group separation was achieved. Effective separation and analysis of oxidation products of coal in aqueous NaOCl solution, established by the study, is a feasible method for high value-added use of coal.

One pot three component synthesis of 9-arylpolyhydroacridine derivatives in an ionic liquid medium

In this paper the preparation of 3,3,6,6-tetramethyl-9-aryl-1,2,3,4,5,6,7,8,9,10- decahydroacridin-1,8-dione derivatives from aromatic aldehydes, 5,5-dimethyl-1,3- cyclohexanedione and ammonium acetate in ionic liquids [bmim+][BF4-] is described. This new method has the advantages of easier work-up, milder reaction conditions, high yields and an environmentally benign procedure compared with other methods.

Effects of molecular hydrogen and hydrogen donor additives on 1,2-di(1-naphthyl)ethane thermolysis

Abstract The thermolysis of 1,2-di(1-naphthyl)ethane (DNE) under pressurized hydrogen or nitrogen with or without a hydrogen donor additive in decalin was investigated to examine the effects of molecular hydrogen and several hydrogen donor additives on DNE thermolysis. The results show that molecular hydrogen and hydrogen donors play very different roles in DNE thermolysis: molecular hydrogen promotes DNE thermolysis, whereas the addition of a hydrogen donor inhibits DNE thermolysis.

Heat shock protein 72 inhibits c-Jun N-terminal kinase 3 signaling pathway via Akt1 during cerebral ischemia

Although recent researches show that Heat Shock Protein 72 (HSP72) plays an important role in neuronal survival, little knowledge is known about the precise mechanisms during cerebral ischemia/reperfusion (I/R). Our present study investigated the neuroprotective mechanisms of HSP72 against ischemic brain injury induced by cerebral I/R. Mild heat shock pretreatment was employed to induce the overexpression of HSP72 by immersing rats into the water bath at 42°C for 20 min before cerebral I/R. HSP72 antisense oligodeoxynucleotides (ODNs) were used to inhibit HSP72 expression by intracerebroventricular infusion once per day for 3 days before cerebral I/R animal model was induced by four-vessel occlusion for 15 min transient ischemia and then reperfused for various time in Sprague-Dawley rats. Immunoprecipitation and immunoblotting were used to detect the expression of the related proteins. HE-staining and TUNEL-staining were carried out to examine the neuronal death of hippocampal CA1 region. Results showed that mild heat shock could increase the phosphorylation of protein kinase B (Akt), inhibit the assembly of MLK3-MKK7-JNK3 signaling module, diminish the phosphorylation of JNK3 and c-Jun, and decrease the activation of caspase-3. Furthermore, mild heat shock could significantly protect neurons against cerebral I/R. Whereas, all of the aforementioned effects of mild heat shock were reversed by HSP72 antisense ODNs. In summary, our results imply that Akt1 activation is involved in the neuroprotection of HSP72 against ischemic brain injury via suppressing JNK3 signaling pathway and provide a new experimental foundation for stroke therapy.

One‐Step Synthesis of 2‐Amino‐3‐cyano‐4‐ aryl‐1,4,5,6‐tetrahydropyrano[3,2‐c]quinolin‐5‐one Derivatives Using KF–Al2O3 as Catalyst

Abstract A series of 2‐amino‐3‐cyano‐4‐aryl‐1,4,5,6‐tetrahydropyrano[3,2‐c] quinolin‐5‐one derivatives were synthesized by the reaction of arylaldehyde, malononitrile, and 4‐hydroxyquinolin‐2‐one in ethyl alcohol at 80°C catalyzed by KF–Al2O3. The structure of the product was confirmed by x‐ray analysis.