Zhi-Tao Xing

4-(Methyl­sulfan­yl)benzamide oxime

Three solutions were made up, of 4-methylthiobenzonitrile (20 mmol) in ethanol (8 ml), hydroxylamine hydrochloride (20 mmol) in ethanol (6 ml), and potassium carbonate (10 mmol) in water (10 ml). The solutions were mixed and the resulting mixture was refluxed for 24 h. After cooling and filtering, the crude title compound was obtained and this was purified by crystallizing from a mixture of ethanol (6 ml) and water (2 ml). Crystals of (I) suitable for X-ray diffraction were obtained by the slow evaporation of an ethanol solution.

N-(2,6-Dimethylphenyl)-2-{2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]phenoxy}acetamide

2-Chloro-N-(2,6-dimethylphenyl)acetamide (10 mmol) was dissolved in acetone (100 ml) and potassium carbonate (15 mmol) was added. 5-(2-Hydroxyphenyl)-3-(4-fluorophenyl)phenyl-1,2,4-oxadiazole (10 mmol) was then added to the reaction and the resulting mixture was refluxed for 12 h. After cooling and filtration, the crude title compound was obtained and purified by recrystallization from ethyl acetate. Crystals of (I) suitable for X-ray diffraction were obtained by slow evaporation of an ethanol solution.